Bromhexine Impurity 34 CAS 606-00-8
| CAS No. | 606-00-8 |
| Molecular Formula | C8H7Br2NO2 |
| Molecular Weight | 308.95 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Bromhexine Impurity 34 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
As a process- or degradation-related impurity, Bromhexine Impurity 34 (CAS 606-00-8, C8H7Br2NO2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Bromhexine Impurity 34 (C8H7Br2NO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 308.95 g/mol, it falls into the moderately-high-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C8H7Br2NO2 |
| Molecular Weight | 308.95 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
Related Bromhexine Standards
- Bromhexine Impurity 38 (CAS CATO-C4X-106038)
- Bromhexine Impurity 51 (CAS 100669-82-7)
- Bromhexine EP Impurity D (CAS 132004-28-5)
- Bromhexine Impurity N2 (CAS 63471-27-2)
- Bromhexine Impurity 7 (CAS 1631131-52-6)
- Bromhexine Related Compound 2 (CAS 32193-43-4)
- Bromhexine EP Impurity B (CAS 50910-55-9)
- Bromhexine impurity 59 (CAS 100669-81-6)
Recommended Standards
- 2,2,3,3,4,4,5,5-octafluoropentanoyl bromide 376-69-2 5H-Octafluorovaleroyl bromide (CAS 376-69-2)
- [2,4-Dibromo-6-(methyl-NNO-azoxy)phenyl]amine (CAS 474318-78-0)
- N-(2,4-dibromo-5-hydroxyphenyl)acetamide (CAS 98446-58-3)
- 6-Bromo-3,4-dichloro-8-fluoro-2-methylquinoline (CAS 2074702-81-9)
- Abemaciclib Impurity 90 (CAS CATO-C4X-293790)
- Thioctic Acid EP Impurity A (CAS 1204245-29-3)
- Ceftizoxime Impurity 83 (CAS CATO-C4X-179383)
- 2-Benzoyl-N-(2-(4-methylpiperidin-1-yl)-2-oxoethyl)benzenesulfonamide (CAS 931359-83-0)
- 2-(4-Fluorophenoxy)-N-[(1S)-1-(4-methoxyphenyl)ethyl]nicotinamide (CAS 214754-75-3)
- (Z)-Ethyl 2-((dimethylamino)methylene)-3-oxopentanoate (CAS 727383-99-5)
- 2-(Difluoromethyl)-3,6-diiodopyridine-5-sulfonamide (CAS 1805323-90-3)
- Fluorescein-thiourea-PEG6-acid (CAS 2055014-69-0)
- 1,2,4,5-Benzenetetracarboxylic Acid-d6 (CAS 344298-79-9)
- Galanin-Like Peptide (porcine) trifluoroacetate salt (CAS 245114-96-9)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com