Nimesulide EP Impurity A CAS 51765-56-1

Purity >95%In StockPharmacopoeial Impurity Standards
CAS No.51765-56-1
Molecular FormulaC13H11N3O7S
Molecular Weight353.31 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Nimesulide EP Impurity A CAS 51765-56-1 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 353.31 g/mol gives Nimesulide EP Impurity A distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

CATO supplies Nimesulide EP Impurity A (CAS 51765-56-1), a pharmacopoeial impurity reference standard (molecular formula C13H11N3O7S, MW 353.31 g/mol) used for the identification and quantification of trace impurities in APIs.

Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, Nimesulide EP Impurity A is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 353.31 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

As a certified reference material (CRM), Nimesulide EP Impurity A meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC13H11N3O7S
Molecular Weight353.31 g/mol
Purity>95%
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)10.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1971
Nitrogen Atoms3
Sulfur Atoms1

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