Haloperidol Impurity 22 CAS 660844-75-7
| CAS No. | 660844-75-7 |
| Molecular Formula | C21H23ClFNO |
| Molecular Weight | 359.86 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Haloperidol Impurity 22 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Haloperidol Impurity 22 (CAS 660844-75-7) is a certified pharmaceutical impurity reference standard with the molecular formula C21H23ClFNO and a molecular weight of 359.86 g/mol.
Haloperidol Impurity 22 (C21H23ClFNO) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C21H23ClFNO |
| Molecular Weight | 359.86 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Haloperidol Standards
- Haloperidol Impurity 39 (CAS 52669-92-8)
- Haloperidol Impurity 20 (CAS 185626-66-8)
- Haloperidol pyridinium Chloride Impurity (CAS 125785-69-5)
- Haloperidol EP Impurity B (CAS 1391052-53-1)
- Haloperidol (CAS 52-86-8)
- Haloperidol Impurity 15 (CAS CATO-C4X-146115)
- Haloperidol EP Impurity A (CAS 3109-12-4)
- Haloperidol-d4 (CAS 1189986-59-1)
Recommended Standards
- (4-chlorophenyl){4-hydroxy-4-[(4-methylphenoxy)methyl]piperidino}methanone 478248-15-6 KS-00003GCY (CAS 478248-15-6)
- tert-Butyl 4-((6-chloro-2-(methylthio)pyrimidin-4-yl)oxy)piperidine-1-carboxylate (CAS 1261234-62-1)
- tert-butyl N-[(tert-butoxy)carbonyl]-N-(4-chloro-5-cyanopyridin-2-yl)carbamate (CAS 2227205-55-0)
- tert-Butyl 3-((6-chloro-2-(methylthio)pyrimidin-4-yl)oxy)piperidine-1-carboxylate (CAS 1261236-06-9)
- Methyldopa Impurity 11 (CAS CATO-C4X-169311)
- Carfilzomib Impurity 11 (CAS 247068-82-2)
- Minoxidil Impurity 52 (CAS CATO-C4X-170052)
- 2-Chloro-1-fluoro-4-(trifluoromethoxy)benzene (CAS 128540-52-3)
- 6,8-Dibromo-2H-chromene-3-carbaldehyde (CAS 885271-27-2)
- 4-chloro-3-methyl-cinnoline (CAS 173415-33-3)
- Ethyl 2-(2-methyl-4-nitrophenyl)acetate (CAS 50712-66-8)
- RQ 00203078 (CAS 1254205-52-1)
- 2-(4-Aminophenyl)-1-(morpholin-4-yl)ethan-1-one (CAS 926247-33-8)
- Semaglutide Impurity 138 (CAS CATO-C4X-2226138)
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