Beclometasone Dipropionate Monohydrate EP Impurity I CAS 52092-12-3

Purity >95%In StockPharmacopoeial Impurity Standards
CAS No.52092-12-3
Molecular FormulaC28H36O6
Molecular Weight468.58 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Beclometasone Dipropionate Monohydrate EP Impurity I CAS 52092-12-3 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 468.58 g/mol gives Beclometasone Dipropionate Monohydrate EP Impurity I distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

Beclometasone Dipropionate Monohydrate EP Impurity I (CAS 52092-12-3) is a certified pharmaceutical impurity reference standard with the molecular formula C28H36O6 and a molecular weight of 468.58 g/mol.

The molecular framework of Beclometasone Dipropionate Monohydrate EP Impurity I (C28H36O6) is characterized by a steroid core, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

CATO manufactures Beclometasone Dipropionate Monohydrate EP Impurity I under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC28H36O6
Molecular Weight468.58 g/mol
AppearancePale yellow to yellow crystalline powder
Purity>95%
StorageStore at room temperature, protect from light, keep sealed and dry
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)11.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1971

Related Beclometasone Standards

Recommended Standards

Why CATO?