Beclometasone Impurity 48 CAS CATO-C4X-147448
| CAS No. | CATO-C4X-147448 |
| Molecular Formula | C25H35ClO6 |
| Molecular Weight | 466.99 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Beclometasone Impurity 48.
Beclometasone Impurity 48 (CAS CATO-C4X-147448) is a certified pharmaceutical impurity reference standard with the molecular formula C25H35ClO6 and a molecular weight of 466.99 g/mol.
Based on its molecular formula C25H35ClO6, Beclometasone Impurity 48 contains a flavonoid core, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 466.99 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Beclometasone Impurity 48 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C25H35ClO6 |
| Molecular Weight | 466.99 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
Related Beclometasone Standards
- Beclometasone Impurity 27 (CAS CATO-C4X-147427)
- Beclometasone Dipropionate Monohydrate EP Impurity I (CAS 52092-12-3)
- Beclometasone dipropionate EP Impurity A (CAS 69224-79-9)
- Beclometasone dipropionate EP Impurity H (CAS 5534-18-9)
- Beclometasone Impurity 38 (CAS CATO-C4X-147438)
- Beclometasone Impurity 53 (CAS CATO-C4X-147453)
- Beclometasone Dipropionate Monohydrate EP Impurity Q (CAS CATO-C4X-147417)
- Beclometasone Impurity 44 (CAS 18769-20-5)
Recommended Standards
- 2-{2-[2-(4-chlorophenyl)adamantan-2-yl]acetamido}ethyl N-phenylcarbamate (CAS 400085-12-3)
- (+)-Cloprostenol Isopropyl Ester (CAS 157283-66-4)
- 4-Chloro-N-[1-(4-ethyl-5-{[(4-methoxyphenyl)methyl]sulfanyl}-4H-1,2,4-triazol-3-yl)ethyl]benzene-1-sulfonamide (CAS 338954-05-5)
- 2-(4-(5-Chloro-2-methylphenyl)piperazin-1-yl)-7-(4-methoxyphenyl)thieno[3,2-d]pyrimidin-4(1H)-one (CAS 1226430-62-1)
- Spironolactone Impurity 10 (CAS 53866-23-2)
- Calcipotriol Impurity 21 (CAS 143032-85-3)
- Butenafine Impurity 12 (CAS 88-03-9)
- 3-Chloro-5-(difluoromethyl)-2-iodopyridin-4-amine (CAS 1806829-35-5)
- Acetophenone-DNPH (CAS 1677-87-8)
- Methyl 3,3-dimethoxy-2-methylpropanoate (CAS 76526-43-7)
- N-(4-(5-Phenyl-1H-1,2,3-triazol-1-yl)phenyl)benzamide (CAS 89779-04-4)
- 4-((P-tolylimino)methyl)phenol (CAS 3230-51-1)
- ethyl piperazine-2-carboxylate dihydrochloride (CAS 129798-91-0)
- Peptide YY (3-36) (canine, mouse, porcine, rat) trifluoroacetate salt (CAS 126339-09-1)
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