Tranexamic Impurity 11 CAS 5264-40-4
| CAS No. | 5264-40-4 |
| Molecular Formula | C8H5Cl3O2 |
| Molecular Weight | 239.48 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system, Tranexamic Impurity 11 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 239.48 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO supplies Tranexamic Impurity 11 (CAS 5264-40-4), a pharmacopoeial impurity reference standard (molecular formula C8H5Cl3O2, MW 239.48 g/mol) used for the identification and quantification of trace impurities in APIs.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Tranexamic Impurity 11 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H5Cl3O2 |
| Molecular Weight | 239.48 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Halogen Content | Cl-containing |
Related Tranexamic Standards
- Tranexamic Impurity 27 (CAS CATO-C4X-177127)
- Tranexamic Impurity 26 (CAS CATO-C4X-177126)
- Tranexamic Acid RC 7 (CAS 180046-62-2)
- Tranexamic Impurity 38 (CAS CATO-C4X-177138)
- Tranexamic Impurity 19 (CAS 5278-91-1)
- Tranexamic Impurity 21 (CAS 195370-52-6)
- Tranexamic Impurity 41 (CAS CATO-C4X-177141)
- Tranexamic Impurity 39 (CAS CATO-C4X-177139)
Recommended Standards
- Topiramate Impurity 13 (CAS 86569-78-0)
- Dotinurad Impurity 115 (CAS CATO-C4X-2494115)
- Diclofenac impurity 6 (CAS 860541-55-5)
- Dotinurad Impurity 117 (CAS CATO-C4X-2494117)
- Pregnenolone Impurity 13 (CAS 68520-34-3)
- Methylene blue Impurity 3 (CAS 34185-21-2)
- Rosuvastatin Impurity 45 (CAS 1821422-50-7)
- 2-Hydroxy-5-(Trifluoromethyl)Pyridine (CAS 33252-63-0)
- (3-Amino-6-chloropyrazin-2-yl)(phenyl)methanone (CAS 56414-04-1)
- 4'-Phenyl-2,2':6',2''-terpyridine (CAS 58345-97-4)
- 4-Bromo-10,11-dihydro-5H-dibenzo[a,d][7]annulen-5-one (CAS 885269-90-9)
- 3-Phenylcyclobutanol (CAS 92243-56-6)
- Leucogen Impurity 4 (CAS CATO-C4X-28894)
- Semaglutide Impurity 167 (CAS CATO-C4X-2226167)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com