Lenvatinib Impurity 24 CAS 52671-64-4

Purity >95%In StockPharmacopoeial Impurity Standards
CAS No.52671-64-4
Molecular FormulaC6H6ClNO
Molecular WeightN/A
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Lenvatinib Impurity 24 CAS 52671-64-4 chemical structure

Description

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

CATO supplies Lenvatinib Impurity 24 (CAS 52671-64-4), a pharmacopoeial impurity reference standard (molecular formula C6H6ClNOHCl, MW 180.03 g/mol) used for the identification and quantification of trace impurities in APIs.

Lenvatinib Impurity 24 (C6H6ClNOHCl) contains an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

As a certified reference material (CRM), Lenvatinib Impurity 24 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC6H6ClNO HCl
Molecular Weight180.03 g/mol
AppearanceWhite to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity>95%
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)3.0
UV AbsorptionUV-absorbing
CAS Registry Year (est.)1972
Halogen ContentCl-containing
Nitrogen Atoms1

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