Sulindac Impurity 90 CAS 53933-60-1
| CAS No. | 53933-60-1 |
| Molecular Formula | 2*C20H17FO3S |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Sulindac Impurity 90 (CAS 53933-60-1, C20H17FO3S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C20H17FO3S, Sulindac Impurity 90 contains a steroid core, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 356.41 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | 2*C20H17FO3S |
| Molecular Weight | 356.41 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1972 |
| Halogen Content | F-containing |
| Sulfur Atoms | 1 |
Related Sulindac Standards
- Sulindac Sulfide Methyl Ester (CAS 106647-49-8)
- Sulindac EP Impurity D (CAS 134439-52-4)
- (S)-Sulindac (CAS 149116-77-8)
- (R)-Sulindac (CAS 190967-68-1)
- Sulindac EP Impurity C-d3 (CAS 250608-66-3)
- Sulindac EP Impurity B-d3 (CAS 250608-67-4)
- Sulindac EP Impurity C (CAS 32004-67-4)
- Sulindac Impurity 89 (CAS 37794-15-3)
Recommended Standards
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- 2'-Deoxy-2'-fluorocytidine hydrate (CAS 1820580-34-4)
- Semaglutide impurity 194 (CAS CATO-C4X-2226194)
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