Avatrombopag Impurity N2 CAS 54127-29-6

Purity 97%+In StockPharmacopoeial Impurity Standards
CAS No.54127-29-6
Molecular FormulaC6H2Cl3NO
Molecular Weight210.45 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Avatrombopag Impurity N2 CAS 54127-29-6 chemical structure

Description

The occurrence of Avatrombopag Impurity N2 is closely related to an amide group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

CATO supplies Avatrombopag Impurity N2 (CAS 54127-29-6), a pharmacopoeial impurity reference standard (molecular formula C6H2Cl3NO, MW 210.45 g/mol) used for the identification and quantification of trace impurities in APIs.

Owing to an amide group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system, Avatrombopag Impurity N2 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 210.45 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

CATO manufactures Avatrombopag Impurity N2 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC6H2Cl3NO
Molecular Weight210.45 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1972
Halogen ContentCl-containing
Nitrogen Atoms1

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