Estriol impurity 25 CAS 55105-93-6
| CAS No. | 55105-93-6 |
| Molecular Formula | C25H30N2O4S |
| Molecular Weight | 454.58 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Estriol impurity 25 (C25H30N2O4S) contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO supplies Estriol impurity 25 (CAS 55105-93-6), a pharmacopoeial impurity reference standard (molecular formula C25H30N2O4S, MW 454.58 g/mol) used for the identification and quantification of trace impurities in APIs.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C25H30N2O4S |
| Molecular Weight | 454.58 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1972 |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Estriol Standards
- Estriol 16-Glucuronide (CAS 1852-50-2)
- Estriol Impurity 27 (CAS 7219-89-8)
- Estriol Impurity 11 (CAS 690996-27-1)
- Estriol Impurity 13 (CAS CATO-C4X-163713)
- Estriol Impurity 15 (CAS CATO-C4X-163715)
- Estriol Triacetate (CAS 2284-32-4)
- Estriol Impurity 26 (CAS CATO-C4X-163726)
- Estriol impurity 24 (CAS 104202-84-8)
Recommended Standards
- n-(2-Ethylphenyl)-4-methyl-5-phenyl-2-(2-phenylacetamido)thiophene-3-carboxamide (CAS 6078-91-7)
- Cilastatin Impurity 37 (CAS CATO-C4X-196037)
- 1-(4-(1-(4-Fluorophenyl)-1H-indol-3-yl)butyl)-3H-spiro[isobenzofuran-1,4-piperidine] (CAS 147817-50-3)
- H-Arg(Pbf)-OEt (CAS 1801580-32-4)
- N-Nitroso Desloratadine Impurity 57 (CAS CATO-C4X-143057)
- Bezafibrate Impurity 9 (CAS 84491-96-3)
- Cefradine Impurity 23 (CAS CATO-C4X-121523)
- 5-Amino-6-bromo-3-chloropicolinonitrile (CAS 488713-32-2)
- 2-(2-Ethoxybenzylidene)-6-hydroxybenzofuran-3(2h)-one (CAS 623122-68-9)
- 7-Fluorobenzo[e][1,2,4]triazin-3-amine (CAS 74916-44-2)
- Tetrabenazine Impurity 21 (CAS 4747-99-3)
- Ticagrelor Impurity 181 (CAS CATO-C4X-1093181)
- 4-Hydroxy Nonenal Mercapturic Acid (CAS 146764-24-1)
- Galanin-Like Peptide (human) trifluoroacetate salt (CAS 245114-99-2)
Why CATO?
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