Estriol Impurity 11 CAS 690996-27-1

Purity 97%+In StockPharmacopoeial Impurity Standards
CAS No.690996-27-1
Molecular FormulaC27H31BrO3
Molecular Weight483.44 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Estriol Impurity 11 CAS 690996-27-1 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 483.44 g/mol gives Estriol Impurity 11 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

CATO supplies Estriol Impurity 11 (CAS 690996-27-1), a pharmacopoeial impurity reference standard (molecular formula C27H31BrO3, MW 483.44 g/mol) used for the identification and quantification of trace impurities in APIs.

Based on its molecular formula C27H31BrO3, Estriol Impurity 11 contains a steroid core, a hydroxyl group, an ether linkage, bromine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 483.44 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

CATO manufactures Estriol Impurity 11 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC27H31BrO3
Molecular Weight483.44 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor)
Purity97%+
StorageStore at room temperature, protect from light, keep sealed and dry
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)12.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1985
Halogen ContentBr-containing

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