Gliclazide EP Impurity C CAS 5577-13-9
| CAS No. | 5577-13-9 |
| Molecular Formula | C10H13NO4S |
| Molecular Weight | 243.28 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Gliclazide EP Impurity C (C10H13NO4S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Gliclazide EP Impurity C (CAS 5577-13-9) is a certified pharmaceutical impurity reference standard with the molecular formula C10H13NO4S and a molecular weight of 243.28 g/mol.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H13NO4S |
| Molecular Weight | 243.28 g/mol |
| Purity | >90% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Gliclazide Standards
- Gliclazide Impurity 2 (Methyl Tosylcarbamate) (CAS 14437-03-7)
- Gliclazide Impurity 8 (CAS 39051-77-9)
- Gliclazide Impurity 16 (CAS CATO-C4X-144916)
- Gliclazide Impurity 11 (CAS 640-61-9)
- Gliclazide EP Impurity D (CAS 1136426-19-1)
- Gliclazide EP Impurity A (CAS 70-55-3)
- Gliclazide EP Impurity E (CAS 1808087-53-7)
- Gliclazide EP Impurity G (CAS CATO-C4X-14497)
Recommended Standards
- Flurbiprofen impurity 120 (CAS 87657-78-1)
- Timolol Impurity 14 (CAS 58827-68-2)
- Glipizide Impurity 43 (CAS CATO-C4X-140743)
- Lifitegrast Impurity 116 (CAS CATO-C4X-2409116)
- Leuprorelin impurity 36 (CAS 1926163-25-8)
- Melphalan Impurity 38 (CAS CATO-C4X-198838)
- Lamivudine EP Impurity H (CAS 160552-54-5)
- 2-Bromo-3-(chloromethyl)-5-(difluoromethyl)-6-fluoropyridine (CAS 1805234-22-3)
- [2-(Benzoylamino)-1,3-thiazol-4-yl]acetic acid (CAS 329698-00-2)
- 7H-Pyrazolo[3,4-b]pyrazine (CAS 399-62-2)
- Isonicotinic Acid Vanillylidenehydrazide (CAS 149-17-7)
- 2,2,2-trifluoroethyl 1-isopropyl-1H-pyrazol-5-ylcarbamate (CAS 1334023-30-1)
- Tetraethyl propane-1,1,2,3-tetracarboxylate (CAS 635-03-0)
- Semaglutide impurity 85 (CAS CATO-C4X-222685)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com