Erlotinib impurity 130 CAS 585-79-5
| CAS No. | 585-79-5 |
| Molecular Formula | C6H4BrNO2 |
| Molecular Weight | 202.01 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Erlotinib impurity 130 (C6H4BrNO2) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, bromine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO supplies Erlotinib impurity 130 (CAS 585-79-5), a pharmacopoeial impurity reference standard (molecular formula C6H4BrNO2, MW 202.01 g/mol) used for the identification and quantification of trace impurities in APIs.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Erlotinib impurity 130 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C6H4BrNO2 |
| Molecular Weight | 202.01 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
Related Erlotinib Standards
- Erlotinib Impurity 105 (CAS 33432-52-9)
- Erlotinib Impurity 87 (CAS CATO-C4X-106987)
- Erlotinib Impurity 123 (CAS 1145671-36-8)
- Erlotinib Impurity 61 (CAS 20825-87-0)
- Erlotinib Impurity 78 (CAS 174674-93-2)
- Erlotinib Impurity 79 (CAS 382150-30-3)
- Erlotinib Impurity 112 (CAS 555-68-0)
- Erlotinib Impurity 84 (CAS 16064-15-6)
Recommended Standards
- 1-Bromo-4-nitrobenzene (CAS 586-78-7)
- Nicergoline EP Impurity D (CAS 20826-04-4)
- N-(2-Bromopyrimidin-5-yl)formamide (CAS 56621-86-4)
- 1-Bromo-2-Nitrobenzene (CAS 577-19-5)
- Apalutamide Impurity 43 (CAS 1513700-34-9)
- LCZ-696 Impurity 27 (CAS 2459446-54-7)
- Pitavastatin Impurity N1 (CAS 147511-70-4)
- Pomalidomide-PEG3-C2-NH2 (TFA) (CAS 2414913-97-4)
- N1-(2-Methoxybenzyl)-N2-(2-(2-phenylmorpholino)ethyl)oxalamide (CAS 954025-47-9)
- S-Adenosyl-L-Methionine Disulfate Tosylate (CAS 97540-22-2)
- 2-Methylacridine (CAS 613-15-0)
- Methyl 2-(((4-cyano-5-methylisothiazol-3-yl)thio)methyl)benzoate (CAS 338778-07-7)
- Methyl 5-chloro-3-methoxypicolinate (CAS 1256805-22-7)
- Semaglutide Impurity 18 (CAS 1671100-14-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com