Ibuprofen Impurity 53 CAS CATO-C4X-108253
| CAS No. | CATO-C4X-108253 |
| Molecular Formula | C14H20O2 |
| Molecular Weight | 220.31 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Ibuprofen Impurity 53 (CAS CATO-C4X-108253) is a certified pharmaceutical impurity reference standard with the molecular formula C14H20O2 and a molecular weight of 220.31 g/mol.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system, Ibuprofen Impurity 53 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 220.31 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Ibuprofen Impurity 53 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H20O2 |
| Molecular Weight | 220.31 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at room temperature |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
Related Ibuprofen Standards
- Ibuprofen Methyl Ester (CAS 61566-34-5)
- Ibuprofen EP Impurity J (CAS 65813-55-0)
- Ibuprofen EP Impurity J (CAS CATO-C4X-1082148)
- Ibuprofen EP Impurity L (CAS 53949-53-4)
- Ibuprofen EP Impurity M (CAS 60057-62-7)
- Ibuprofen Impurity 27 (CAS 53949-54-5)
- (S)-(+)-Ibuprofen Acid Chloride (CAS 115588-20-0)
- Ibuprofen Impurity 58 (CAS 80336-66-9)
Recommended Standards
- 2,2＇-Dipyridyl Disulfide (CAS 2127-03-9)
- methyl 4-(3,4-dimethylphenyl)-3-methylbutanoate (CAS CATO-C3D-262491)
- 5',6',7',8'-tetrahydro-3'H-spiro[cyclohexane-1,2'-quinazolin]-4'(4a'H)-one (CAS CATO-C4X-144915)
- N-(1-ethylpropyl)-N-nitroso-3,4-dimethylbenzeneamine(Mixture of isomers) (CAS CATO-C3D-26156)
- Peptide Impurity 04 (CAS 2913424-91-4)
- Trimetazidine EP Impurity D (CAS 71989-96-3)
- Ceftriaxone Impurity 51 (CAS CATO-C4X-116351)
- Ziprasidone impurity 49 (CAS CATO-C4X-124049)
- (2-Methoxyphenyl)(pyridin-2-yl)methanone (CAS 22945-63-7)
- (2R,3R,4R,5R)-3-benzyloxy-5-(benzyloxymethyl)tetrahydrofuran-2,4-diol (CAS 1583259-13-5)
- 3-Azabicyclo[4.1.0]Heptane-2-carboxylic acid (CAS 1779637-15-8)
- 2,5-Dichloro-4-(difluoromethyl)-3-methoxypyridine (CAS 1805333-09-8)
- Budesonide EP Impurity G (Mixture of Epimer) (CAS 137174-25-5)
- Peptide Impurity (CAS CATO-CPTD788810)
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