Ibuprofen Impurity 58 CAS 80336-66-9
| CAS No. | 80336-66-9 |
| Molecular Formula | C13H17ClO |
| Molecular Weight | 224.73 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Ibuprofen Impurity 58 (C13H17ClO) contains a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO supplies Ibuprofen Impurity 58 (CAS 80336-66-9), a pharmacopoeial impurity reference standard (molecular formula C13H17ClO, MW 224.73 g/mol) used for the identification and quantification of trace impurities in APIs.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C13H17ClO |
| Molecular Weight | 224.73 g/mol |
| Purity | >95% |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1979 |
| Halogen Content | Cl-containing |
Related Ibuprofen Standards
- (S)-(+)-Ibuprofen Acid Chloride (CAS 115588-20-0)
- Ibuprofen Impurity 74 (CAS 1261642-35-6)
- Ibuprofen Impurity 26 (CAS 67173-18-6)
- Ibuprofen Impurity 51 (CAS 43153-03-3)
- Ibuprofen EP Impurity L (CAS 53949-53-4)
- Ibuprofen EP Impurity M (CAS 60057-62-7)
- Ibuprofen Impurity 27 (CAS 53949-54-5)
- Ibuprofen EP Impurity B Sodium (CAS CATO-C4X-108236)
Recommended Standards
- 898785-26-7 6-Chloro-1-(3-methylphenyl)hexan-1-one DTXSID00642368 (CAS 898785-26-7)
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- (R)-Ethyl 5-amino-3-hydroxypentanoate (CAS 182955-76-6)
- Roxadustat Impurity 35 (CAS 2370958-34-0)
- 2-Pivaloylcyclohexan-1-one (CAS 41043-87-2)
- 3-Chloro-5-(2-chloropyridin-4-yl)-1,2,4-oxadiazole (CAS 1393575-87-5)
- 14333-34-7 Gadolinium, isotope of mass 155 Gadolinium-155 105Gd (CAS 14333-34-7)
- 6-Phenyl-1-benzofuran (CAS 35664-69-8)
- FMRF-Like Neuropeptide (CAS 121801-61-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com