Doxazosin Impurity 15 CAS 60547-96-8
| CAS No. | 60547-96-8 |
| Molecular Formula | C10H12N4O2 |
| Molecular Weight | 220.23 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Doxazosin Impurity 15 (C10H12N4O2) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO supplies Doxazosin Impurity 15 (CAS 60547-96-8), a pharmacopoeial impurity reference standard (molecular formula C10H12N4O2, MW 220.23 g/mol) used for the identification and quantification of trace impurities in APIs.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Doxazosin Impurity 15 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H12N4O2 |
| Molecular Weight | 220.23 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1974 |
| Nitrogen Atoms | 4 |
Related Doxazosin Standards
- Doxazosin Impurity 19 (CAS CATO-C4X-162319)
- Doxazosin EP Impurity D (CAS 28888-44-0)
- Doxazosin Impurity 2 (CAS 4739-94-0)
- Doxazosin EP Impurity F (CAS 23680-84-4)
- Doxazosin Impurity 10 (CAS 3663-79-4)
- Doxazosin EP Impurity E (CAS 27631-29-4)
- Doxazosin EP Impurity A (CAS 3663-80-7)
- Doxazosin Impurity 20 (CAS CATO-C4X-162320)
Recommended Standards
- 89454-68-2 ACMC-20lmdn Benzonitrile, 3-(1H-imidazo[4,5-b]pyridin-2-yl)- (CAS 89454-68-2)
- Theophylline Impurity 16 (CAS CATO-C4X-182316)
- 89454-67-1 Benzonitrile, 4-(1H-imidazo[4,5-b]pyridin-2-yl)- DTXSID40356972 (CAS 89454-67-1)
- Carbazochrome Impurity N7 (CAS 70063-07-9)
- Sofosbuvir Impurity 102 (CAS CATO-C4X-1052102)
- Abemaciclib Impurity 47 (CAS CATO-C4X-293747)
- Isotretinoin EP Impurity I (CAS 75281-25-3)
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- N-[(1S)-1-(1-Naphthalenyl)ethyl]-3-(trifluoromethyl)benzenepropanamide (CAS 955371-05-8)
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- Semaglutide impurity 248 (CAS CATO-C4X-2226248)
Why CATO?
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