Neostigmine impurity 01 CAS 618-09-7
| CAS No. | 618-09-7 |
| Molecular Formula | C8H11NO3S |
| Molecular Weight | 201.24 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, Neostigmine impurity 01 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 201.24 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO supplies Neostigmine impurity 01 (CAS 618-09-7), a pharmacopoeial impurity reference standard (molecular formula C8H11NO3S, MW 201.24 g/mol) used for the identification and quantification of trace impurities in APIs.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Neostigmine impurity 01 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H11NO3S |
| Molecular Weight | 201.24 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Neostigmine Standards
- Neostigmine impurity 35 (CAS CATO-C4X-204235)
- Neostigmine Impurity 25 (CAS 76418-45-6)
- Neostigmine impurity 34 (CAS CATO-C4X-204234)
- Neostigmine impurity 36 (CAS CATO-C4X-204236)
- Neostigmine EP Impurity C (CAS 16088-19-0)
- Neostigmine impurity 38 (CAS CATO-C4X-204238)
- Neostigmine Bromide EP Impurity C-d6 (Nor Neostigmine-d6) (CAS 2470126-73-7)
- Neostigmine Impurity 26 (CAS 4849-46-1)
Recommended Standards
- Naphtho[1,2-d][1,3]oxazole-2-thiol (CAS 51793-90-9)
- N-ethyl-4-hydroxybenzenesulfonamide (CAS 3271-43-0)
- N-[3-(Hydroxymethyl)phenyl]methanesulfonamide (CAS 376347-09-0)
- N-Methyl-O-tosylhydroxylamine (CAS 25370-97-2)
- Cyproterone Acetate EP Impurity I (CAS 13698-49-2)
- Mirogabalin Impurity 37 (CAS CATO-C4X-292437)
- Hydroxychloroquine Impurity 70 (CAS 56881-09-5)
- 3-(2-(Thietan-3-ylamino)ethyl)imidazolidine-2,4-dione (CAS 1873234-73-1)
- Condurango glycoside A (CAS 11051-90-4)
- 5-(Bis(4-methoxybenzyl)amino)-6-methyl-1H-pyrrolo[3,2-b]pyridine-2-carboxylic acid (CAS 2891456-66-7)
- 8-chloro-3,4-dihydro-2H-1-benzopyran-4-ol (CAS 1176104-70-3)
- 2-Chloro-N,N-diphenylethanethioamide (CAS 57988-98-4)
- (S)-alpha-(4-Chlorophenyl)benzylamine hydrochloride, 97% (CAS 451503-28-9)
- Insulin Degludec Impurity 26 (CAS CATO-C4X-215726)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com