Azathioprine Impurity 21 CAS 30467-02-8
| CAS No. | 30467-02-8 |
| Molecular Formula | C6H8N4O |
| Molecular Weight | 152.15 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Owing to an amide group, a hydroxyl group, an ether linkage, an aromatic ring system, Azathioprine Impurity 21 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 152.15 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a process- or degradation-related impurity, Azathioprine Impurity 21 (CAS 30467-02-8, C6H8N4O) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Azathioprine Impurity 21 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C6H8N4O |
| Molecular Weight | 152.15 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1965 |
| Nitrogen Atoms | 4 |
Related Azathioprine Standards
- Azathioprine EP Impurity B (CAS 157930-13-7)
- Azathioprine EP Impurity B (CAS 50-44-2)
- Azathioprine Impurity 12 (CAS 1192-53-6)
- Azathioprine Impurity N4 (CAS 5167-18-0)
- Azathioprine Impurity 9 (CAS 1190008-04-8)
- Azathioprine EP Impurity D (CAS 6339-54-4)
- Azathioprine EP Impurity C (CAS 4897-25-0)
- Azathioprine EP Impurity A (CAS 4531-54-8)
Recommended Standards
- Deferasirox EP Impurity F (CAS 619-67-0)
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- Oseltamivir Impurity 80 (CAS 793667-32-0)
- Vortioxetine Impurity 137 (CAS CATO-C4X-1056137)
- Olopatadine Impurity 49 (CAS CATO-C4X-171849)
- 5-Chloro-2-cyclopropoxybenzenesulfonamide (CAS 1243360-27-1)
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- 6-ethoxy-4-hydroxy-1,5-naphthyridine-3-carboxylic acid (CAS 92808-09-8)
- Cefpirome Impurity 4 (CAS CATO-C4X-12074)
- Hepcidin/LEAP-1 (Human); Liver-Expressed Antimicrobial Peptide (CAS 342790-21-0)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com