Azathioprine EP Impurity B CAS 157930-13-7
| CAS No. | 157930-13-7 |
| Molecular Formula | C5H4N4S |
| Molecular Weight | 152.18 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Azathioprine EP Impurity B is closely related to a nitrile group, sulfur-containing functionality in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies Azathioprine EP Impurity B (CAS 157930-13-7), a pharmacopoeial impurity reference standard (molecular formula C5H4N4S, MW 152.18 g/mol) used for the identification and quantification of trace impurities in APIs.
Azathioprine EP Impurity B (C5H4N4S) contains a nitrile group, sulfur-containing functionality. Its physicochemical properties are representative of its class; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Azathioprine EP Impurity B meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C5H4N4S |
| Molecular Weight | 152.18 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 2002 |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Azathioprine Standards
- Azathioprine EP Impurity B (CAS 50-44-2)
- Azathioprine Impurity 21 (CAS 30467-02-8)
- Azathioprine Impurity 12 (CAS 1192-53-6)
- Azathioprine Impurity N4 (CAS 5167-18-0)
- Azathioprine Impurity 9 (CAS 1190008-04-8)
- Azathioprine EP Impurity D (CAS 6339-54-4)
- Azathioprine EP Impurity C (CAS 4897-25-0)
- Azathioprine EP Impurity A (CAS 4531-54-8)
Recommended Standards
- [1,2,4]Triazolo[4,3-a]pyrazine-3-thiol (CAS 1517917-09-7)
- 9H-purine-6-thiol (CAS 157930-14-8)
- 3-(1,3-thiazol-2-yl)-4H-1,2,4-triazole (CAS 1340241-97-5)
- 6-Amino-1,2-dihydro-2-thioxo-5-pyrimidinecarbonitrile (CAS 16462-26-3)
- Peramivir impurity 138 (CAS CATO-C4X-1833138)
- Atrasentan Impurity 73 (CAS 1058404-70-8)
- Finasteride Impurity 25 (CAS 172922-52-0)
- 2,2,2-Trifluoroethyl n-(furan-2-ylmethyl)carbamate (CAS 875157-18-9)
- 4-Chloro-2-ethyl-5-((4-methoxybenzyl)oxy)pyridazin-3(2H)-one (CAS 88094-00-2)
- 1H-Azepine,hexahydro-2-(3-methylphenyl)- 383129-36-0 CTK4H9683 (CAS 383129-36-0)
- (2E)-2-[2-(Quinolin-8-yl)hydrazin-1-ylidene]propanoic acid hydrochloride (CAS 477762-38-2)
- 2-(tert-Butyl)-3-cyclopropoxy-5-methoxypyridine (CAS 1243409-09-7)
- Apixaban Impurity 133 (CAS CATO-C4X-1088133)
- (Leu31,Pro3?)-Neuropeptide Y (porcine) trifluoroacetate salt (CAS 125580-28-1)
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