Capecitabine Impurity 28 CAS 862508-03-0
| CAS No. | 862508-03-0 |
| Molecular Formula | C10H14FN3O3 |
| Molecular Weight | 243.23 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO supplies Capecitabine Impurity 28 (CAS 862508-03-0), a pharmacopoeial impurity reference standard (molecular formula C10H14FN3O3, MW 243.23 g/mol) used for the identification and quantification of trace impurities in APIs.
Capecitabine Impurity 28 (C10H14FN3O3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), Capecitabine Impurity 28 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H14FN3O3 |
| Molecular Weight | 243.23 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Capecitabine Standards
- Capecitabine EP Impurity A (CAS 66335-38-4)
- Capecitabine Impurity 16 (CAS CATO-C4X-102416)
- Capecitabine Impurity 18 (CAS 71609-08-0)
- Capecitabine EP Impurity B (CAS 3094-09-5)
- Capecitabine Impurity 46 (CAS 34980-66-0)
- Capecitabine Impurity 19 (CAS CATO-C4X-102419)
- Capecitabine Impurity 12 (CAS 62211-93-2)
- Capecitabine Impurity 14 (CAS 76497-54-6)
Recommended Standards
- MEthyl 5-fluoro-3h-benzo[e]indole-2-carboxylate (CAS 887361-23-1)
- Tedizolid Impurity 41 (CAS CATO-C4X-105441)
- 4-(2,4-Difluorophenyl)thiomorpholine-3,5-dione (CAS 338793-79-6)
- 4-(Carbamoylmethanesulfonyl)benzoic acid (CAS 1016709-80-0)
- Imrecoxib Impurity 17 (CAS CATO-C4X-237917)
- Peramivir Impurity 45 (CAS CATO-C4X-183345)
- Tofacitinib Impurity 164 (CAS 71607-31-3)
- Methyl 6-ethoxy-1H-indole-5-carboxylate (CAS 672293-17-3)
- 2-Chloro-1-(6-fluorobenzo[b]thiophen-2-yl)ethanone (CAS 1533073-40-3)
- (S)-2-(Pyridin-2-ylthio)propanoic acid (CAS 864754-02-9)
- 4-Hydroxy-N-(2-hydroxypropyl)benzamide (CAS 98034-09-4)
- 5-fluoropyridine-3-boronic acid (CAS 872041-86-6)
- 1-(3-(tert-Butyl)-1H-1,2,4-triazol-1-yl)ethanone (CAS 132408-61-8)
- [y-Glu3]-Semaglutide Impurity 135 (CAS CATO-C4X-2226135)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com