Citalopram Impurity 68 CAS 481047-48-7
| CAS No. | 481047-48-7 |
| Molecular Formula | C20H23FN2O2 |
| Molecular Weight | 342.41 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Citalopram Impurity 68 is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Citalopram Impurity 68 (CAS 481047-48-7) is a certified pharmaceutical impurity reference standard with the molecular formula C20H23FN2O2 and a molecular weight of 342.41 g/mol.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, Citalopram Impurity 68 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 342.41 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Citalopram Impurity 68 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C20H23FN2O2 |
| Molecular Weight | 342.41 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Citalopram Standards
- Citalopram EP Impurity A (CAS 64372-56-1)
- Citalopram Impurity 11 (CAS CATO-C4X-110911)
- Citalopram Impurity 14 (CAS CATO-C4X-110914)
- Citalopram Impurity 15 (CAS 488787-59-3)
- Citalopram Impurity 84 (CAS CATO-C4X-110984)
- Citalopram EP Impurity M (CAS 440121-09-5)
- Citalopram Nitrile Oxide (CAS 1346601-93-1)
- Citalopram EP Impurity B (Escitalopram EP Impurity B ) (CAS 411221-53-9)
Recommended Standards
- Escitalopram EP Impurity A(R-Isomer) (CAS CATO-C4X-110920)
- Sildenafil Impurity 296 (CAS CATO-C4X-1128296)
- Captopril Impurity 30 (CAS CATO-C4X-119030)
- Escitalopram Impurity 2 (CAS 103146-25-4)
- (E)-Cilnidipine Impurity 15 (CAS CATO-C4X-179615)
- Blonanserin Impurity 12 (CAS 142838-82-2)
- Rosuvastatin Impurity 142 (CAS CATO-C4X-1169142)
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- Methyl 3-(3-bromo-5-fluorophenyl)-2-hydroxypropanoate (CAS 1509855-68-8)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com