Citalopram Impurity 11 CAS CATO-C4X-110911
| CAS No. | CATO-C4X-110911 |
| Molecular Formula | C20H23FN2O2 |
| Molecular Weight | 342.41 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Citalopram Impurity 11 (C20H23FN2O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a process- or degradation-related impurity, Citalopram Impurity 11 (CAS CATO-C4X-110911, C20H23FN2O2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Citalopram Impurity 11 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C20H23FN2O2 |
| Molecular Weight | 342.41 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Citalopram Standards
- Citalopram EP Impurity A (CAS 64372-56-1)
- Citalopram Impurity 14 (CAS CATO-C4X-110914)
- Citalopram Impurity 15 (CAS 488787-59-3)
- Citalopram Impurity 68 (CAS 481047-48-7)
- Citalopram Impurity 84 (CAS CATO-C4X-110984)
- Citalopram EP Impurity M (CAS 440121-09-5)
- Citalopram Nitrile Oxide (CAS 1346601-93-1)
- Citalopram EP Impurity B (Escitalopram EP Impurity B ) (CAS 411221-53-9)
Recommended Standards
- Alogliptin Impurity 51 (CAS 1133421-35-8)
- Ethyl 4-((2-methoxy-5-methylphenyl)sulfonyl)piperazine-1-carboxylate (CAS 681852-57-3)
- Escitalopram EP Impurity A(R-Isomer) (CAS CATO-C4X-110920)
- 2-Ethoxy-5-((4-ethylpiperazin-1-yl)sulfonyl)benzoic acid (CAS 1245644-35-2)
- Difelikefalin Impurity 98 (CAS CATO-C4X-304198)
- Osimertinib Impurity 68 (CAS CATO-C4X-204568)
- Tamsulosin Impurity 44 (CAS 119714-13-5)
- 1-(Sec-butyl)-2-nitrobenzene (CAS 19370-34-4)
- 2,4-Dihydroxybenzaldehyde (CAS 95-01-2)
- Methyl 5-(bromomethyl)-4,5-dihydro-1,2-oxazole-3-carboxylate (CAS 1423034-24-5)
- 2-Morpholinothiazole-4-carboxylic acid (CAS 906353-04-6)
- 2-(1-Hydroxy-1,3-dihydrobenzo[c][1,2]oxaborol-7-yl)acetic acid (CAS 1268335-32-5)
- 2,2-DIMETHYL-2,3-DIHYDROQUINOLIN-4(1H)-ONE (CAS 132588-91-1)
- Biotinyl-Pancreatic Polypeptide (human) trifluoroacetate salt (CAS 1816258-36-2)
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