Citalopram EP Impurity B (Escitalopram EP Impurity B ) CAS 411221-53-9
| CAS No. | 411221-53-9 |
| Molecular Formula | C20H21FN2O2 |
| Molecular Weight | 340.39 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Citalopram EP Impurity B (Escitalopram EP Impurity B ) (CAS 411221-53-9) is a certified pharmaceutical impurity reference standard with the molecular formula C20H21FN2O2 and a molecular weight of 340.39 g/mol.
Structurally, Citalopram EP Impurity B (Escitalopram EP Impurity B ) (C20H21FN2O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 11.0, corresponding to approximately 11 ring(s) or double-bond equivalent(s). With a molecular weight of 340.39 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Citalopram EP Impurity B (Escitalopram EP Impurity B ) under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C20H21FN2O2 |
| Molecular Weight | 340.39 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Citalopram Standards
- Citalopram Nitrile Oxide (CAS 1346601-93-1)
- (R)-Citalopram N-Oxide (CAS 1217761-31-3)
- Citalopram EP Impurity C (CAS 372941-54-3)
- Citalopram EP Impurity A (CAS 64372-56-1)
- Citalopram Impurity 11 (CAS CATO-C4X-110911)
- Citalopram Impurity 14 (CAS CATO-C4X-110914)
- Citalopram Impurity 15 (CAS 488787-59-3)
- Citalopram Impurity 68 (CAS 481047-48-7)
Recommended Standards
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- 1-(2-fluorophenyl)-3,5-dimethylpyrazole (CAS 1153039-39-4)
- tert-butyl (1R,4R,5S)-5-amino-2-azabicyclo[2.1.1]hexane-2-carboxylate (CAS 1932212-66-2)
- Isavuconazole Impurity N12 (CAS 2732924-98-8)
- Ethyl 5,7-dimethyl-2-oxo-2H-chromene-3-carboxylate (CAS 25816-59-5)
- Methyl 2'-oxo-3,4-dihydro-1h-spiro[naphthalene-2,3'-piperidine]-6-carboxylate (CAS 2028324-91-4)
- Tirzepatide(sodium salt) (CAS 2023788-19-2(free base))
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com