Linagliptin Impurity 18 CAS 668273-74-3
| CAS No. | 668273-74-3 |
| Molecular Formula | C30H36N8O4 |
| Molecular Weight | 572.66 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Linagliptin Impurity 18 (CAS 668273-74-3) is a certified pharmaceutical impurity reference standard with the molecular formula C30H36N8O4 and a molecular weight of 572.66 g/mol.
The molecular framework of Linagliptin Impurity 18 (C30H36N8O4) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Linagliptin Impurity 18 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C30H36N8O4 |
| Molecular Weight | 572.66 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 17.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Nitrogen Atoms | 8 |
Related Linagliptin Standards
- Linagliptin Impurity 123 (CAS CATO-C4X-1101123)
- Linagliptin impurity 143 (CAS 2517759-32-7)
- Linagliptin Impurity 159 (CAS CATO-C4X-1101159)
- Linagliptin Impurity 46 (CAS 668273-75-4)
- Linagliptin Impurity 69 (CAS CATO-C4X-110169)
- Linagliptin Impurity 77 (CAS 1673546-62-7)
- Linagliptin Impurity N13 (CAS 2138392-83-1)
- Linagliptin Impurity 12 (CAS CATO-C4X-110112)
Recommended Standards
- Bradykinin (1-5) (CAS 23815-89-6)
- Atorvastatin Impurity 16 (CAS CATO-C4X-113216)
- N-[6-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanoyl]-L-valyl-N5-carbamoyl-N-[4-(hydroxymethyl)phenyl]-L-ornithinamide (CAS 159857-80-4)
- Atorvastatin Calcium EP Impurity M (CAS 345891-62-5)
- Phytomenadione/Vitamin K1 Impurity 89 (CAS CATO-C4X-220789)
- Dotinurad Impurity 162 (CAS CATO-C4X-2494162)
- Roflumilast Impurity 52 (CAS CATO-C4X-108452)
- 2-{5-methylimidazo[1,2-a]pyridin-2-yl}ethan-1-amine dihydrobromide (CAS 1909314-35-7)
- (2S)-2-(Chloromethyl)-4-(phenylmethyl)morpholine (CAS 1222556-84-4)
- 2-(2-Fluoro-4-methoxyphenyl)propan-2-ol (CAS 96826-25-4)
- (2R,3R,4S,5R)-2-(6-Amino-8-methyl-2-(methylthio)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol (CAS 65991-09-5)
- 4-Methoxy-5-nitronicotinonitrile (CAS 1806295-45-3)
- tert-Butyl (1-((S)-2-aminopropanoyl)pyrrolidin-3-yl)carbamate (CAS 1354026-57-5)
- Liraglutide (CAS 204656-20-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com