Beclometasone Impurity 43 CAS CATO-C4X-147443
| CAS No. | CATO-C4X-147443 |
| Molecular Formula | C28H36O7 |
| Molecular Weight | 484.58 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
As a process- or degradation-related impurity, Beclometasone Impurity 43 (CAS CATO-C4X-147443, C28H36O7) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, a polycyclic aromatic system, Beclometasone Impurity 43 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 484.58 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C28H36O7 |
| Molecular Weight | 484.58 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | ≥95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
Related Beclometasone Standards
- Beclometasone Dipropionate Monohydrate EP Impurity Q (CAS CATO-C4X-147417)
- Beclometasone Impurity 53 (CAS CATO-C4X-147453)
- Beclometasone Impurity 51 (CAS CATO-C4X-147451)
- Beclometasone Impurity 38 (CAS CATO-C4X-147438)
- Beclometasone Dipropionate Monohydrate EP Impurity I (CAS 52092-12-3)
- Beclometasone Impurity 27 (CAS CATO-C4X-147427)
- Beclometasone Impurity 48 (CAS CATO-C4X-147448)
- Beclometasone dipropionate EP Impurity A (CAS 69224-79-9)
Recommended Standards
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