Betamethasone impurity 59 CAS CATO-C4X-143759
| CAS No. | CATO-C4X-143759 |
| Molecular Formula | C22H32FO9P |
| Molecular Weight | 490.46 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Betamethasone impurity 59 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Betamethasone impurity 59 (CAS CATO-C4X-143759) is a certified pharmaceutical impurity reference standard with the molecular formula C22H32FO9P and a molecular weight of 490.46 g/mol.
Structurally, Betamethasone impurity 59 (C22H32FO9P) contains a phosphate ester group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 6.5, corresponding to approximately 6 ring(s) or double-bond equivalent(s). With a molecular weight of 490.46 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C22H32FO9P |
| Molecular Weight | 490.46 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
Related Betamethasone Standards
- Betamethasone Dipropionate EP Impurity D (CAS 5514-81-8)
- Betamethasone Impurity 76 (CAS 5534-01-0)
- Betamethasone Succinate (CAS 27297-42-3)
- Betamethasone Valerate EP Impurity H (CAS 52619-18-8)
- Betamethasone Impurity 43 (CAS 4735-65-3)
- Betamethasone impurity 52 (CAS 97168-90-6)
- Betamethasone impurity 67 (CAS 13796-49-1)
- Betamethasone Dipropionate EP Impurity F (CAS 66917-44-0)
Recommended Standards
- (3R,4R,5R)-3,5-Bis(3,4,5-trihydroxyphenylcarbonyloxy)-4-hydroxycyclohex-1-enecarboxylic acid (3R,4S,5R)-4-hydroxy-3,5-bis[(3,4,5-trihydroxybenzoyl)oxy]cyclohexene-1-carboxylic acid 3,5-Di-O-galloylshikimic acid 95753-52-9 Benzoic acid, 3,4,5-trihydroxy-, (1R,2S,3R)-5-carboxy-2-hydroxy-4-cyclohexene-1,3-diyl ester GN-11 (CAS 95753-52-9)
- 6-Chloro-2,8-diiodo-9-(tetrahydro-2H-pyran-2-yl)-9H-purine (CAS 1262785-79-4)
- 3,4-Di-o-galloylshikimicacid 95753-51-8 (CAS 95753-51-8)
- [4-(1,3-Benzothiazol-2-ylsulfanyl)-3-nitrophenyl]methyl 3-(trifluoromethyl)benzoate (CAS 320424-22-4)
- Lornoxicam Impurity 80 (CAS CATO-C4X-201680)
- N-Nitroso Minocycline EP Impurity C (CAS 28698-93-3)
- Mosapride Impurity 71 (CAS CATO-C4X-104471)
- Ethyl 2-((4-aminocyclohexyl)oxy)acetate (CAS 1564649-71-3)
- (2S,3S)-3-Methylpyrrolidine-2-carboxylic acid (CAS 10512-89-7)
- 1-{[3-(benzyloxy)phenyl]methyl}piperazine (CAS 523980-09-8)
- tert-Butyl ((benzyloxy)carbonyl)-L-threoninate (CAS 72289-51-1)
- 5-Chloro-2-(piperidin-3-ylmethyl)-1H-benzimidazole (CAS 936074-52-1)
- Methyl 3-methoxy-5-(trifluoromethyl)picolinate (CAS 1804099-09-9)
- Semaglutide Impurity 6 (CAS 62-57-7)
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