Miconazole EP Impurity G CAS 909277-71-0
| CAS No. | 909277-71-0 |
| Molecular Formula | C18H14Cl4N2O |
| Molecular Weight | 416.13 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Miconazole EP Impurity G (CAS 909277-71-0) is a certified pharmaceutical impurity reference standard with the molecular formula C18H14Cl4N2O and a molecular weight of 416.13 g/mol.
Structurally, Miconazole EP Impurity G (C18H14Cl4N2O) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 11.0, corresponding to approximately 11 ring(s) or double-bond equivalent(s). With a molecular weight of 416.13 g/mol, it falls into the moderately-high-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C18H14Cl4N2O |
| Molecular Weight | 416.13 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Miconazole Standards
- Miconazole EP Impurity D (CAS 27523-40-6)
- Miconazole EP Impurity F (CAS 47447-55-2)
- Miconazole (CAS 22916-47-8)
- Miconazole impurity 34 (CAS CATO-C4X-180234)
- Miconazole Impurity N1 (CAS 911805-54-4)
- Miconazole Impurity 15 (CAS 913837-72-6)
- Miconazole EP Impurity I (CAS 47363-37-1)
- Miconazole EP Impurity C (CAS 67358-54-7)
Recommended Standards
- 4-(4-Iodophenoxy)-2-(trifluoromethyl)quinazoline (CAS 339018-48-3)
- (S)-1-(2-((2,4-Dichlorobenzyl)oxy)-2-(2,4-dichlorophenyl)ethyl)-1H-imidazole (CAS 47447-52-9)
- 1,3-Dibromo-7-tert-butylpyrene (CAS 1005771-04-9)
- (R)-1-(2-((2,4-Dichlorobenzyl)oxy)-2-(2,4-dichlorophenyl)ethyl)-1H-imidazole (CAS 47447-53-0)
- Piperazine impurity 49 (CAS 3029270-07-0)
- Ponatinib Impurity 29 (CAS CATO-C4X-226929)
- Thioctic Acid Impurity 24 (CAS CATO-C4X-152653)
- Methyl 4-oxo-4-((phenylselanyl)oxy)butanoate (CAS 676259-99-7)
- 3-Bromo-6-chloro-2-methyl-1H-pyrrolo[2,3-b]pyridine (CAS 1936487-25-0)
- 3,8-dioxa-1-azaspiro[4.5]decan-2-one (CAS 1497905-45-9)
- (R)-2-((4-(2-Methoxyethyl)phenoxy)methyl)oxirane (CAS 133397-54-3)
- 3,4-dimethylpyrrolidin-2-one (CAS 39585-10-9)
- Methyl 2-amino-6-propyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylate (CAS 1021014-97-0)
- Semaglutide Impurity 189 (CAS CATO-C4X-2226189)
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