Miconazole Impurity N1 CAS 911805-54-4
| CAS No. | 911805-54-4 |
| Molecular Formula | C16H13Cl4NO2 |
| Molecular Weight | 393.09 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Miconazole Impurity N1 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies Miconazole Impurity N1 (CAS 911805-54-4), a pharmacopoeial impurity reference standard (molecular formula C16H13Cl4NO2, MW 393.09 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Miconazole Impurity N1 (C16H13Cl4NO2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C16H13Cl4NO2 |
| Molecular Weight | 393.09 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Miconazole Standards
- Miconazole Impurity 15 (CAS 913837-72-6)
- Miconazole EP Impurity I (CAS 47363-37-1)
- Miconazole EP Impurity D (CAS 27523-40-6)
- Miconazole EP Impurity F (CAS 47447-55-2)
- Miconazole EP Impurity G (CAS 909277-71-0)
- Miconazole (CAS 22916-47-8)
- Miconazole impurity 34 (CAS CATO-C4X-180234)
- Miconazole EP Impurity C (CAS 67358-54-7)
Recommended Standards
- 4-(2,4-Dichlorophenoxy)-N-(3,5-dichlorophenyl)butanamide (CAS 303091-87-4)
- 2,2,2-Trichloro-1-(4-(7-chloroquinolin-4-yl)piperazin-1-yl)ethanone (CAS 104667-94-9)
- 3,4-Dichloro-N-[2,4-dichloro-5-(propan-2-yloxy)phenyl]benzamide (CAS 338961-14-1)
- 2,4-Difluoro-6-((2-fluoro-4-iodophenyl)amino)benzoic acid (CAS 934665-14-2)
- Levofloxacin Impurity 80 (CAS CATO-C4X-137180)
- Brivaracetam Impurity 34 (CAS CATO-C4X-200734)
- Orbifloxacin EP Impurity D (CAS 126458-22-8)
- 4-(4-Chlorophenyl)-6-(3,4-dichlorophenyl)-2-hydroxypyridine-3-carbonitrile (CAS 79325-11-4)
- 2-Methyl-n-(pyridin-4-yl)furan-3-carboxamide (CAS 35498-44-3)
- Crisaborole Impurity 19 (CAS CATO-C4X-202119)
- 6'-(Diethylamino)-3'-hydroxy-3-oxo-3H-spiro[isobenzofuran-1,9'-xanthene]-2'-carboxylic acid (CAS 6359-29-1)
- 4-Methyl-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazole-2-carboxylic acid (CAS 1314986-72-5)
- 5-Chloro-2-morpholino-6-nitrooxazolo[4,5-b]pyridine (CAS 1801345-37-8)
- Semaglutide Impurity 7 (CAS CATO-C4X-22267)
Why CATO?
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