Bumetanide Impurity 40 CAS 688047-82-7
| CAS No. | 688047-82-7 |
| Molecular Formula | C17H17NO3 |
| Molecular Weight | 283.32 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Bumetanide Impurity 40 (C17H17NO3) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Bumetanide Impurity 40 (CAS 688047-82-7) is a certified pharmaceutical impurity reference standard with the molecular formula C17H17NO3 and a molecular weight of 283.32 g/mol.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Bumetanide Impurity 40 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C17H17NO3 |
| Molecular Weight | 283.32 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Nitrogen Atoms | 1 |
Related Bumetanide Standards
- Bumetanide Impurity 78 (CAS CATO-C4X-198678)
- Bumetanide Impurity 78 (CAS CATO-C4X-198679)
- Bumetanide Impurity 7 (CAS 130262-91-8)
- Bumetanide Impurity 25 (CAS 105641-65-4)
- Bumetanide Impurity 45 (CAS 61658-42-2)
- Bumetanide Impurity 133 (CAS CATO-C4X-1986133)
- Bumetanide Impurity 48 (CAS CATO-C4X-198648)
- Bumetanide Impurity 5 (CAS 22892-96-2)
Recommended Standards
- Tolvaptan Impurity 54 (CAS 1118884-66-4)
- Metaraminol Impurity 94 (CAS CATO-C4X-225294)
- Adrenaline Impurity 86 (CAS CATO-C4X-184986)
- Nefopam Impurity 21 (CAS CATO-C4X-283721)
- Lemborexant Impurity 53 (CAS CATO-C4X-304253)
- Delafloxacin impurity 39 (CAS CATO-C4X-263739)
- Amorolfine Impurity 58 (CAS CATO-C4X-154258)
- 2-(3-Bromobenzyl)pyrrolidine (CAS 1226033-42-6)
- 2-Bromo-1-(4-bromo-2-methoxyphenyl)ethanone (CAS 252561-75-4)
- (R)-3-Amino-3-(4-bromophenyl)propan-1-ol (CAS 1213037-93-4)
- Ruxolitinib Impurity 224 (CAS CATO-C4X-2058224)
- 2-Cyclobutyl-1,3-thiazole-5-carbaldehyde (CAS 1394042-39-7)
- 4-(Methoxymethyl)bicyclo[2.2.2]Octan-1-amine hydrochloride (CAS 2231672-93-6)
- Semaglutide Impurity 144 (CAS 394210-59-4)
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