Bumetanide Impurity 78 CAS CATO-C4X-198679
| CAS No. | CATO-C4X-198679 |
| Molecular Formula | C18H21NO2 |
| Molecular Weight | 283.36 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Bumetanide Impurity 78 (C18H21NO2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Bumetanide Impurity 78 (CAS CATO-C4X-198679) is a certified pharmaceutical impurity reference standard with the molecular formula C18H21NO2 and a molecular weight of 283.36 g/mol.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Bumetanide Impurity 78 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H21NO2 |
| Molecular Weight | 283.36 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 1 |
Related Bumetanide Standards
- Bumetanide Impurity 78 (CAS CATO-C4X-198678)
- Bumetanide Impurity 40 (CAS 688047-82-7)
- Bumetanide Impurity 7 (CAS 130262-91-8)
- Bumetanide Impurity 25 (CAS 105641-65-4)
- Bumetanide Impurity 45 (CAS 61658-42-2)
- Bumetanide Impurity 133 (CAS CATO-C4X-1986133)
- Bumetanide Impurity 48 (CAS CATO-C4X-198648)
- Bumetanide Impurity 5 (CAS 22892-96-2)
Recommended Standards
- Ebastine Impurity 25 (CAS CATO-C4X-202925)
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- Tadalafil Impurity 158 (CAS 1863191-32-5)
- Lusutrombopag Impurity 27 (CAS CATO-C4X-208427)
- Cefaclor Impurity 35 (CAS CATO-C4X-127035)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com