Chlortetracycline EP Impurity H CAS 7301-38-4
| CAS No. | 7301-38-4 |
| Molecular Formula | C23H24ClNO8 |
| Molecular Weight | 477.89 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Chlortetracycline EP Impurity H is closely related to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Chlortetracycline EP Impurity H (CAS 7301-38-4) is a certified pharmaceutical impurity reference standard with the molecular formula C23H24ClNO8 and a molecular weight of 477.89 g/mol.
Chlortetracycline EP Impurity H (C23H24ClNO8) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Chlortetracycline EP Impurity H under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C23H24ClNO8 |
| Molecular Weight | 477.89 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1959 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chlortetracycline Standards
- Chlortetracycline EP Impurity G (CAS 769895-23-0)
- Chlortetracycline EP Impurity A (CAS 14297-93-9)
- Chlortetracycline Hydrochloride EP Impurity F (CAS CATO-C4X-233023)
- Chlortetracycline Impurity 24 (CAS CATO-C4X-233024)
- Chlortetracycline Hydrochloride EP Impurity K (CAS CATO-C4X-233021)
- Chlortetracycline Hydrochloride EP Impurity L (CAS CATO-C4X-233022)
- Chlortetracycline hydrochloride (CAS 64-72-2)
- Chlortetracycline EP Impurity A HCl (CAS 101342-45-4)
Recommended Standards
- 4-(4-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxy}phenyl)-N-(4-methoxyphenyl)-1,3-thiazol-2-amine (CAS 1024375-85-6)
- N-(9-((2R,3R,4R,5R)-3-(1-(2-Chloroethoxy)ethoxy)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9H-purin-6-yl)benzamide (CAS 138078-24-7)
- 4-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)methyl)phenyl naphthalene-2-sulfonate (CAS 338415-85-3)
- Neratinib Impurity 31 (CAS CATO-C4X-113431)
- Roxadustat Impurity 54 (CAS CATO-C4X-221354)
- Azilsartan Impurity 134 (CAS 57113-88-9)
- Ixazomib Impurity 82 (CAS CATO-C4X-126782)
- 5-fluoroimidazo[1,2-a]pyridine-3-carboxylic acid (CAS 1783619-07-7)
- Methyl 2-amino-4-(2,4-dichlorophenyl)-5-methylthiophene-3-carboxylate (CAS 350989-98-9)
- tert-Butyl (2-((4-aminophenyl)amino)-2-oxoethyl)carbamate (CAS 83209-85-2)
- 5-(chloromethyl)-1-methyl-imidazole (CAS 89180-90-5)
- Methyl (1R,2S,3R,4S)-3-aminobicyclo[2.2.1]heptane-2-carboxylate (CAS 1071523-44-8)
- Methyl 3-amino-5-bromo-4-methylbenzoate (CAS 223519-11-7)
- Casein kinase II peptide Substrate (CAS 154444-98-1)
Why CATO?
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