Chlorpheniramine Impurity 16 CAS 73775-50-5
| CAS No. | 73775-50-5 |
| Molecular Formula | C12H15ClN2 |
| Molecular Weight | 222.71 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Chlorpheniramine Impurity 16 (CAS 73775-50-5, C12H15ClN2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Chlorpheniramine Impurity 16 (C12H15ClN2) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Chlorpheniramine Impurity 16 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H15ClN2 |
| Molecular Weight | 222.71 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1978 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Chlorpheniramine Standards
- Chlorpheniramine Impurity 12 (CAS 20619-13-0)
- Chlorpheniramine Impurity 19 (CAS CATO-C4X-118819)
- Chlorpheniramine Impurity 36 (CAS CATO-C4X-118836)
- Chlorpheniramine Impurity 38 (CAS CATO-C4X-118838)
- Chlorpheniramine Impurity 41 (CAS 101286-08-2)
- Chlorpheniramine (CAS 132-22-9)
- Chlorpheniramine-d6 (CAS 1185054-60-7)
- Chlorpheniramine Impurity 14 (CAS CATO-C4X-118814)
Recommended Standards
- 1-p-Tolyl-cyclopentanecarbonyl chloride 1-p-tolylcyclopentanecarbonyl chloride 82278-33-9 (CAS 82278-33-9)
- Thioctic Acid Impurity 8 (CAS 1070-65-1)
- (3-Chlorophenyl)cyclohexylmethanone 211985-77-2 3-Chlorophenyl cyclohexyl ketone (CAS 211985-77-2)
- Thioctic acid Impurity 28 (CAS 947236-49-9)
- Sodium Valproate Impurity 39 (CAS CATO-C4X-116639)
- Lidocaine Impurity 87 (CAS CATO-C4X-167987)
- Estradiol Impurity 25 (CAS 4245-41-4)
- 4-Methyl-N-(2-((4-methyl-1,2,3-thiadiazol-5-yl)thio)ethyl)benzamide (CAS 478063-51-3)
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- [2,2'-Bis(diphenylphosphino)-1,1-binaphthyl]rhodium(I)(cyclooctadiene) tetrafluoroborate (CAS 439801-50-0)
- dimethyl[2-(pyrrolidin-2-yl)ethyl]amine dihydrochloride (CAS 1909316-17-1)
- 1-Ethyl-4-hydroxypiperidine (CAS 3518-83-0)
- (4-(Hydroxyimino)piperidin-1-yl)(pyridin-4-yl)methanone (CAS 1017043-97-8)
- 302798-54-5 (Leu31,Pro34)-Neuropeptide Y (13-36) (human, rat) MFCD00672463 (CAS 302798-54-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com