Tamoxifen EP Impurity B CAS 748-97-0
| CAS No. | 748-97-0 |
| Molecular Formula | C26H31NO2 |
| Molecular Weight | 389.53 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Tamoxifen EP Impurity B (C26H31NO2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage. Its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a process- or degradation-related impurity, Tamoxifen EP Impurity B (CAS 748-97-0, C26H31NO2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Tamoxifen EP Impurity B under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C26H31NO2 |
| Molecular Weight | 389.53 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Nitrogen Atoms | 1 |
Related Tamoxifen Standards
- Tamoxifen N-Oxide (CAS 75504-34-6)
- Tamoxifen impurity 19 (CAS CATO-C4X-123319)
- Tamoxifen Impurity 15 (CAS 157698-32-3)
- Tamoxifen Citrate Impurity 25 (CAS 114828-90-9)
- Tamoxifen 2-Isomer (CAS 7728-73-6)
- Tamoxifen EP Impurity A (CAS 13002-65-8)
- Tamoxifen Impurity 29 (CAS CATO-C4X-123329)
- Tamoxifen EP Impurity E (Mixture of Z and E Isomers) (CAS CATO-C4X-12336)
Recommended Standards
- Mifepristone Impurity 11 (CAS CATO-C4X-121611)
- Atomoxetine Impurity 46 (CAS CATO-C4X-155046)
- Terbutaline impurity 105 (CAS CATO-C4X-1183105)
- Atomoxetine Impurity 54 (CAS CATO-C4X-155054)
- Tacrolimus impurity 71 (CAS CATO-C4X-130071)
- Osimertinib Impurity 109 (CAS CATO-C4X-2045109)
- Semaglutide impurity 49 (CAS CATO-C4X-222649)
- Ethyl 2-oxo-2-(o-tolyl)acetate (CAS 66644-67-5)
- 448376BFQC 673-32-5 1-Phenyl-1-propyne Prop-1-ynylbenzene EINECS 211-607-7 UNII-448376BFQC (CAS 673-32-5)
- (5-(Butylcarbamoyl)-2-chlorophenyl)boronic acid (CAS 2096336-21-7)
- 2,3-Dimethyl-1,3,8-triazaspiro[4.5]Dec-1-en-4-one hydrochloride (CAS 1774899-05-6)
- 2002-03-1 5-Phenyl-1,3,4-thiadiazol-2-amine DTXSID80277076 (CAS 2002-03-1)
- 2-(6-Nitrobenzo[d][1,3]dioxol-5-yl)quinazolin-4(3H)-one (CAS 942888-20-2)
- Semaglutide Impurity 185 (CAS CATO-C4X-2226185)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com