Nitrendipine impurity 21 CAS 1195583-65-3
| CAS No. | 1195583-65-3 |
| Molecular Formula | C17H16N2O6 |
| Molecular Weight | 344.32 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Nitrendipine impurity 21 (CAS 1195583-65-3), a pharmacopoeial impurity reference standard (molecular formula C17H16N2O6, MW 344.32 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, Nitrendipine impurity 21 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 344.32 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Nitrendipine impurity 21 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C17H16N2O6 |
| Molecular Weight | 344.32 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Nitrogen Atoms | 2 |
Related Nitrendipine Standards
- Nitrendipine Impurity 3 (CAS 76258-20-3)
- Nitrendipine Impurity 7 (CAS 89267-42-5)
- Nitrendipine Impurity 4 (CAS CATO-C4X-18344)
- Nitrendipine Impurity 5 (CAS 74936-73-5)
- Nitrendipine EP Impurity A (CAS 89267-41-4)
- Nitrendipine Impurity 2 (CAS CATO-C4X-18342)
- (+)-Nitrendipine (CAS 80890-07-9)
- Nitrendipine (CAS 39562-70-4)
Recommended Standards
- Nintedanib Impurity 99 (CAS CATO-C4X-181499)
- Nifedipine EP Impurity A (CAS 67035-22-7)
- 214843-13-7 Coccineone E (CAS 214843-13-7)
- Bifendate Impurity 4 (CAS CATO-C4X-25554)
- Sertraline EP Impurity D (CAS 2378750-29-7)
- Latamoxef Impurity 16 (CAS CATO-C4X-179816)
- Chlorhexidine Impurity 19 (CAS CATO-C4X-225619)
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- Eledoisin Related Peptide (CAS 2990-43-4)
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