Norfloxacin EP Impurity E(Hydrochloride) CAS 75001-78-4
| CAS No. | 75001-78-4 |
| Molecular Formula | C16H18ClN3O3 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO supplies Norfloxacin EP Impurity E(Hydrochloride) (CAS 75001-78-4), a pharmacopoeial impurity reference standard (molecular formula C16H18ClN3O3HCl, MW 372.25 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Norfloxacin EP Impurity E(Hydrochloride) is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 372.25 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO manufactures Norfloxacin EP Impurity E(Hydrochloride) under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H18ClN3O3 HCl |
| Molecular Weight | 372.25 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >90% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1978 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Norfloxacin Standards
- Norfloxacin-D5 (CAS 1015856-57-1)
- Norfloxacin Impurity 21 (CAS 103240-27-3)
- Norfloxacin Hydrochloride (CAS 104142-93-0)
- Norfloxacin EP Impurity H (CAS 105440-01-5)
- Norfloxacin Impurity C70 (CAS 106847-38-5)
- Norfloxacin Impurity C171 (CAS 106847-39-6)
- Norfloxacin Impurity 63 (CAS 106847-42-1)
- Norfloxacin Impurity 22 (CAS 109142-49-6)
Recommended Standards
- Itraconazole Impurity 100 (CAS CATO-C4X-1497100)
- Lusutrombopag Impurity 6 (CAS 1110767-77-5)
- Haloperidol impurity 02 (CAS 121751-79-9)
- (R)-1-(3,4-dimethoxyphenyl)propan-1-amine hydrochloride (CAS 2061996-87-8)
- 1-Ethyl-1H-imidazole-4,5-dicarboxylic acid (CAS 86263-61-8)
- 1-(4-(((6-Methylquinolin-2-yl)methylene)amino)phenyl)ethanone (CAS 89060-07-1)
- Dimethyl Chlorophosphite (CAS 3743-07-5)
- 8-Bromo-5-methyl-5H-[1,2,4]triazino[5,6-b]indole-3-thiol (CAS 23563-33-9)
- Cefaclor EP Impurity C (CAS 143059-69-2)
- Peptide Impurity 82 (CAS 10491-78-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com