Olsalazine EP Impurity B CAS 752188-68-4
| CAS No. | 752188-68-4 |
| Molecular Formula | C14H10N2O6 |
| Molecular Weight | 302.24 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a process- or degradation-related impurity, Olsalazine EP Impurity B (CAS 752188-68-4, C14H10N2O6) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, Olsalazine EP Impurity B is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 302.24 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H10N2O6 |
| Molecular Weight | 302.24 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Nitrogen Atoms | 2 |
Related Olsalazine Standards
- Olsalazine-d3,15N sodium (CAS 15722-48-2)
- Olsalazine-13C6 (CAS CATO-C4X-180110)
- Olsalazine EP Impurity A (CAS CATO-C4X-18011)
- Olsalazine EP Impurity D (CAS 93964-55-7)
- Olsalazine EP Impurity C (CAS 259151-72-9)
- Olsalazine EP Impurity E (CAS CATO-C4X-18015)
- Olsalazine EP Impurity I (CAS CATO-C4X-18019)
- Olsalazine EP Impurity F (CAS CATO-C4X-18016)
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