Levothyroxine sulfate CAS 77074-49-8
| CAS No. | 77074-49-8 |
| Molecular Formula | C15H11I4NO7S |
| Molecular Weight | 856.93 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Levothyroxine sulfate (CAS 77074-49-8) is a high-purity analytical reference standard with the molecular formula C15H11I4NO7S and a molecular weight of 856.93 g/mol.
Structurally, Levothyroxine sulfate (C15H11I4NO7S) contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, iodine substitution. The molecule exhibits a degree of unsaturation (DBE) of 9.0, corresponding to approximately 9 ring(s) or double-bond equivalent(s). With a molecular weight of 856.93 g/mol, it falls into the high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C15H11I4NO7S |
| Molecular Weight | 856.93 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1979 |
| Halogen Content | I-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Levothyroxine Standards
- Levothyroxine Impurity N90 (CAS 30804-52-5)
- Levothyroxine Impurity 54 (CAS CATO-C4X-167854)
- Levothyroxine Impurity 4 (CAS 910907-23-2)
- Levothyroxine N-Acetyl Impurity (CAS 26041-51-0)
- Levothyroxine (CAS CATO-C4X-167855)
- Levothyroxine Ethyl Ester (CAS 76353-71-4)
- Levothyroxine Impurity 51 (CAS CATO-C4X-167851)
- Levothyroxine Impurity 27 (CAS 671235-41-9)
Recommended Standards
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- (2S)-2-(pyridin-3-ylformamido)propanoic acid (CAS 36724-75-1)
- Methyl 6-(aminomethyl)-4-iodopicolinate (CAS 1393555-67-3)
- (1,10-Phenanthroline)(1,2-octanediolato)Pd(II) (CAS 1219966-88-7)
- 1-Aminonaphthalene-2-boronic acid (CAS 1621965-01-2)
- 2-(3-Bromophenyl)-9-phenylcarbazole (CAS 1365118-41-7)
- Semaglutide impurity 267 (CAS CATO-C4X-2226267)
Why CATO?
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