Levothyroxine Impurity 54 CAS CATO-C4X-167854
| CAS No. | CATO-C4X-167854 |
| Molecular Formula | C18H16I4N2O5S |
| Molecular Weight | 880.01 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Levothyroxine Impurity 54.
Levothyroxine Impurity 54 (CAS CATO-C4X-167854) is a certified pharmaceutical impurity reference standard with the molecular formula C18H16I4N2O5S and a molecular weight of 880.01 g/mol.
Based on its molecular formula C18H16I4N2O5S, Levothyroxine Impurity 54 contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, iodine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 880.01 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H16I4N2O5S |
| Molecular Weight | 880.01 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | I-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Levothyroxine Standards
- Levothyroxine (CAS CATO-C4X-167855)
- Levothyroxine sulfate (CAS 77074-49-8)
- Levothyroxine Impurity 51 (CAS CATO-C4X-167851)
- Levothyroxine Impurity N90 (CAS 30804-52-5)
- Levothyroxine Impurity 50 (CAS CATO-C4X-167850)
- Levothyroxine Impurity 4 (CAS 910907-23-2)
- Levothyroxine Impurity 29（Mixture of Diastereomers） (CAS CATO-C4X-167829)
- Levothyroxine N-Acetyl Impurity (CAS 26041-51-0)
Recommended Standards
- Piperacillin Impurity 83 (CAS CATO-C4X-173283)
- des-Orn8-Atosiban (CAS CATO-C4X-229372)
- trans-Iodo(p-nitrophenyl)bis(triphenylphosphine)palladium (CAS 33377-47-8)
- FeTCPP (CAS 55266-17-6)
- Aztreonam impurity 62 (CAS CATO-C4X-152262)
- Paricalcitol Impurity 44 (CAS CATO-C4X-138744)
- Pretomanid Impurity 4 (CAS 1131004-99-3)
- N1-(2-Methyl-6-morpholinopyrimidin-4-yl)benzene-1,4-diamine (CAS 1402747-67-4)
- 312693-02-0 2-Ethylbutylzinc bromide, 0.5M in THF MFCD01311415 (CAS 312693-02-0)
- 2-(Chloromethyl)-6-hydroxyquinazolin-4(3H)-one (CAS 1258977-05-7)
- N-(furan-2-ylmethyl)pivalamide (CAS 152937-53-6)
- 3-(2,4-Difluorophenyl)-3H-[1,2,3]triazolo[4,5-b]pyridine (CAS 62051-90-5)
- 12-Methyltridecancarbonsaeure 12-Methyltridecansaeure 12-methyltridecanoic acid 12-methyltridecylic acid 2724-57-4 C14:0 iso CHEBI:43722 aseanostatin P1 i14:0 iso-14:0 iso-C14:0 isomyristic acid (CAS 2724-57-4)
- Semaglutide impurity 274 (CAS CATO-C4X-2226274)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com