Levothyroxine Impurity 4 CAS 910907-23-2
| CAS No. | 910907-23-2 |
| Molecular Formula | C21H20I3NO10 |
| Molecular Weight | 827.10 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies Levothyroxine Impurity 4 (CAS 910907-23-2), a certified reference material (molecular formula C21H20I3NO10, MW 827.10 g/mol) for analytical method development and quality control.
Based on its molecular formula C21H20I3NO10, Levothyroxine Impurity 4 contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, iodine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 827.10 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C21H20I3NO10 |
| Molecular Weight | 827.10 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | I-containing |
| Nitrogen Atoms | 1 |
Related Levothyroxine Standards
- Levothyroxine N-Acetyl Impurity (CAS 26041-51-0)
- Levothyroxine Impurity N90 (CAS 30804-52-5)
- Levothyroxine Ethyl Ester (CAS 76353-71-4)
- Levothyroxine Impurity 27 (CAS 671235-41-9)
- Levothyroxine sulfate (CAS 77074-49-8)
- Levothyroxine Impurity 30 (CAS 107849-54-7)
- Levothyroxine impurity 47 (CAS CATO-C4X-167847)
- Levothyroxine Methyl Ester (CAS 32180-11-3)
Recommended Standards
- 3,3',5-Triiodo-L-thyronine 4'-O-β-D-glucuronide, 98% (CAS 29919-72-0)
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- Ginsenoside Rs3 (CAS 194861-70-6)
- CU-HHTP (CAS 2257422-27-6)
- 4-((4-Chloro-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-2-yl)methyl)morpholine (CAS 721414-43-3)
- 5-benzyl-3a-methyl-6,6a-dihydro-4H-furo[3,4-c]pyrrole-1,3-dione (CAS 885956-67-2)
- N-(4-Methylbenzyl)-N-(6-methyl-4-oxo-1,4-dihydropyrimidin-2-yl)guanidine (CAS 1306738-46-4)
- 2,3-diamino-1-phenylbutan-1-ol dihydrochloride (CAS 2060020-52-0)
- n-((4-Bromothiophen-2-yl)methyl)cyclohexanamine (CAS 1040045-85-9)
- 2-(4-(Trifluoromethyl)pyridin-2-yl)acetic acid (CAS 1000515-78-5)
- n-Allyl-2-(2-imino-2,3-dihydrothiazol-4-yl)acetamide (CAS 1019108-38-3)
- (3-Ethoxycarbonylaminophenyl)acetic acid (CAS 741254-28-4)
- 4-Methyl-1-phenyl-1H-pyrazole-3-carboxylic acid (CAS 241798-67-4)
- Insulin Degludec Impurity 25 (CAS CATO-C4X-215725)
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