Halometasone Impurity N2 CAS 80157-55-7
| CAS No. | 80157-55-7 |
| Molecular Formula | C21H25ClF2O5 |
| Molecular Weight | 430.87 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO supplies Halometasone Impurity N2 (CAS 80157-55-7), a pharmacopoeial impurity reference standard (molecular formula C21H25ClF2O5, MW 430.87 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a flavonoid core, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, Halometasone Impurity N2 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 430.87 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a certified reference material (CRM), Halometasone Impurity N2 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C21H25ClF2O5 |
| Molecular Weight | 430.87 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1979 |
| Halogen Content | F/Cl-containing |
Related Halometasone Standards
- Halometasone Impurity 9 (CAS CATO-C4X-14469)
- Halometasone impurity 14 (CAS CATO-C4X-144614)
- Halometasone Impurity 3 (CAS 67212-85-5)
- Halometasone impurity 15 (CAS CATO-C4X-144615)
- Halometasone impurity 17 (CAS 35540-75-1)
- Halometasone Impurity 4 (CAS CATO-C4X-14464)
- Halometasone Impurity 67 (CAS CATO-C4X-14467)
- Halometasone (CAS 50629-82-8)
Recommended Standards
- N-(3-((5-Chloro-2-hydroxyphenyl)amino)quinoxalin-2-yl)-1-methyl-1H-pyrazole-4-sulfonamide (CAS 1795425-41-0)
- 2-(4-(Benzo[d][1,3]dioxol-5-ylmethyl)piperazin-1-yl)-4-(4-chlorophenyl)-4-oxobutanoic acid (CAS 1337915-30-6)
- 4,7-Dibromo-5,6-dinitro-2,1,3-benzoselenadiazole (CAS 711026-22-1)
- Methyl 3-chloro-2-(2-(1-(2-ethoxybenzyl)-1H-imidazol-2-yl)ethyl)-4,6-dihydroxybenzoate (CAS 1887032-92-9)
- Mirogabalin Impurity 7 (CAS 1644251-45-5)
- Trifarotene impurity 21 (CAS CATO-C4X-313221)
- Amlodipine impurity 126 (CAS CATO-C4X-1095126)
- Ethyl 2-(2-cyano-3-(4-isopropylphenyl)acrylamido)-5-phenylthiophene-3-carboxylate (CAS 469872-53-5)
- Resmetirom impurity 76 (CAS CATO-C4X-291276)
- 5-Iodo-4-oxo-1,4-dihydropyridine-3-carbonitrile (CAS 1174709-11-5)
- N-(6-Ethoxybenzo[d]thiazol-2-yl)-3,5-dimethoxybenzamide (CAS 300712-78-1)
- 4-Fluoro-2-isopropylbenzaldehyde (CAS 1289039-02-6)
- Pyridin-3-ylmethyl 8-methoxy-2H-chromene-3-carboxylate (CAS 338419-73-1)
- Anti-Inflammatory Peptide 1 (CAS 118850-71-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com