Halometasone Impurity 67 CAS CATO-C4X-14467

Purity >95%In StockPharmacopoeial Impurity Standards
CAS No.CATO-C4X-14467
Molecular FormulaC22H25ClF2O5
Molecular Weight442.88 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Halometasone Impurity 67 CAS CATO-C4X-14467 chemical structure

Description

The occurrence of Halometasone Impurity 67 is closely related to a flavonoid core, a hydroxyl group, an ether linkage, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

Halometasone Impurity 67 (CAS CATO-C4X-14467) is a certified pharmaceutical impurity reference standard with the molecular formula C22H25ClF2O5 and a molecular weight of 442.88 g/mol.

Based on its molecular formula C22H25ClF2O5, Halometasone Impurity 67 contains a flavonoid core, a hydroxyl group, an ether linkage, fluorine/chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 442.88 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

As a certified reference material (CRM), Halometasone Impurity 67 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC22H25ClF2O5
Molecular Weight442.88 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity>95%
StorageStore at room temperature, protect from light, keep sealed and dry
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)9.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
Halogen ContentF/Cl-containing

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