Halometasone Impurity 4 CAS CATO-C4X-14464
| CAS No. | CATO-C4X-14464 |
| Molecular Formula | C22H25ClF2O5 |
| Molecular Weight | 442.88 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Halometasone Impurity 4 (C22H25ClF2O5) contains a flavonoid core, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO supplies Halometasone Impurity 4 (CAS CATO-C4X-14464), a pharmacopoeial impurity reference standard (molecular formula C22H25ClF2O5, MW 442.88 g/mol) used for the identification and quantification of trace impurities in APIs.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Halometasone Impurity 4 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C22H25ClF2O5 |
| Molecular Weight | 442.88 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F/Cl-containing |
Related Halometasone Standards
- Halometasone impurity 15 (CAS CATO-C4X-144615)
- Halometasone impurity 17 (CAS 35540-75-1)
- Halometasone Impurity 67 (CAS CATO-C4X-14467)
- Halometasone (CAS 50629-82-8)
- Halometasone Impurity 6 (CAS CATO-C4X-14466)
- Halometasone Impurity N2 (CAS 80157-55-7)
- Halometasone Impurity 9 (CAS CATO-C4X-14469)
- Halometasone impurity 14 (CAS CATO-C4X-144614)
Recommended Standards
- 3-{2-[(4-chlorophenyl)methoxy]phenyl}-1-(4-fluorobenzenesulfonyl)-1H-pyrazole (CAS 477713-39-6)
- 7-(3-(((4-Chlorophenyl)sulfonyl)methyl)-4-nitrophenyl)-2-methylpyrazolo[1,5-a]pyrimidine (CAS 691868-58-3)
- Roxadustat Impurity 104 (CAS CATO-C4X-2213104)
- 5-Chloro-4-iodo-1-(triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridine (CAS 1040682-76-5)
- Sulfasalazine Impurity 17 (CAS CATO-C4X-141917)
- Cefotaxime Impurity 65 (CAS CATO-C4X-120165)
- Belumosudil Impurity 65 (CAS CATO-C4X-298865)
- 6-(Trifluoromethyl)isoquinolin-3-ol (CAS 1175271-49-4)
- 4-(4-Isopropoxybenzyl)aniline (CAS 221532-04-3)
- 4,5-Difluoro-1-naphthonitrile (CAS 52692-39-4)
- (2-Chlorophenyl)(cyclopropyl)methanone (CAS 149914-81-8)
- 1-Hydrazinyl-4-(pyridin-4-ylmethyl)phthalazine (CAS 17692-43-2)
- 2-((4-Bromophenyl)amino)-1H-purin-6(9H)-one (CAS 123994-72-9)
- Casein kinase II peptide Substrate (CAS 154444-98-1)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com