Halometasone Impurity 3 CAS 67212-85-5
| CAS No. | 67212-85-5 |
| Molecular Formula | C22H25ClF2O4 |
| Molecular Weight | 426.88 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Halometasone Impurity 3 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Halometasone Impurity 3 (CAS 67212-85-5) is a certified pharmaceutical impurity reference standard with the molecular formula C22H25ClF2O4 and a molecular weight of 426.88 g/mol.
Owing to a flavonoid core, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, Halometasone Impurity 3 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 426.88 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C22H25ClF2O4 |
| Molecular Weight | 426.88 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1976 |
| Halogen Content | F/Cl-containing |
Related Halometasone Standards
- Halometasone impurity 14 (CAS CATO-C4X-144614)
- Halometasone Impurity 9 (CAS CATO-C4X-14469)
- Halometasone Impurity N2 (CAS 80157-55-7)
- Halometasone impurity 15 (CAS CATO-C4X-144615)
- Halometasone impurity 17 (CAS 35540-75-1)
- Halometasone Impurity 4 (CAS CATO-C4X-14464)
- Halometasone Impurity 67 (CAS CATO-C4X-14467)
- Halometasone (CAS 50629-82-8)
Recommended Standards
- N-(5-Chloro-2-((4-methyl-4H-1,2,4-triazol-3-yl)thio)phenyl)-2-(2-oxoquinoxalin-1(2H)-yl)acetamide (CAS 871089-29-1)
- Bis[tris(1-methylethyl)phosphine]palladium (CAS 52359-16-7)
- 4-Chloro-N-(3-((3-hydroxyphenyl)amino)quinoxalin-2-yl)benzenesulfonamide (CAS 299955-10-5)
- BML-190 (CAS 2854-32-2)
- Pyronaridine Impurity 11 (CAS CATO-C4X-297811)
- Ibrutinib Impurity 40 (CAS CATO-C4X-106440)
- Betahistine Impurity 01 DiHCl (CAS 101252-40-8)
- Tert-butyl 4,4-dimethyl-1-oxa-6-azaspiro[2.5]Octane-6-carboxylate (CAS 1955531-11-9)
- 2,5-Di-tert-butylbenzene-1,4-diamine (CAS 22162-01-2)
- 2-(Methylsulfonyl)-4-(tributylstannyl)pyrimidine (CAS 123061-52-9)
- Montelukast Impurity 36 (CAS 142569-69-5)
- 2-[1-(1-Cyclohexen-1-yl)ethenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 306775-14-4)
- 6-Mercapto-2-methylpyrimidin-4-ol (CAS 42956-80-9)
- Semaglutide (CAS CATO-C4X-2226105)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com