Bortezomib Impurity N32 CAS 84110-34-9

Purity >95%In StockPharmacopoeial Impurity Standards
CAS No.84110-34-9
Molecular FormulaC14H25BO2
Molecular Weight236.16 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Bortezomib Impurity N32 CAS 84110-34-9 chemical structure

Description

As a process- or degradation-related impurity, Bortezomib Impurity N32 (CAS 84110-34-9, C14H25BO2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.

Bortezomib Impurity N32 (C14H25BO2) contains a carboxylic acid group, a hydroxyl group, an ether linkage. Its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC14H25BO2
Molecular Weight236.16 g/mol
Purity>95%
StorageStore at room temperature
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityStable under recommended storage conditions
Degree of Unsaturation (DBE)2.5
CAS Registry Year (est.)1981

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