Bortezomib Impurity 11 CAS CATO-C4X-107211
| CAS No. | CATO-C4X-107211 |
| Molecular Formula | C10H16BN3O3 |
| Molecular Weight | 237.06 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Bortezomib Impurity 11 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
As a process- or degradation-related impurity, Bortezomib Impurity 11 (CAS CATO-C4X-107211, C10H16BN3O3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Bortezomib Impurity 11 (C10H16BN3O3) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C10H16BN3O3 |
| Molecular Weight | 237.06 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | >90% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 4.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 3 |
Related Bortezomib Standards
- Bortezomib Impurity N32 (CAS 84110-34-9)
- Bortezomib Impurity 41 (CAS 4664-57-7)
- Bortezomib Impurity 27 (CAS CATO-C4X-107227)
- Bortezomib Impurity 15 (CAS 1259365-04-2)
- Bortezomib Impurity 80 (CAS 179324-86-8)
- Bortezomib Impurity 1 (CAS 289472-80-6)
- Bortezomib Impurity 36 (CAS CATO-C4X-107236)
- Bortezomib Impurity 61 (CAS CATO-C4X-107261)
Recommended Standards
- Methyl 4,5-dichloro-2-fluoro-3-methylbenzoate (CAS 2586126-79-4)
- 2-Boc-aminophenylboronic Acid (CAS 115377-94-1)
- 6-bromo-1-methyl-pyrazolo[4,3-b]pyridine-3-carbonitrile (CAS 2090591-91-4)
- Ethyl 5-bromo-1,3,4-thiadiazole-2-carboxylate (CAS 1030613-07-0)
- Isavuconazole Impurity 15 (CAS CATO-C4X-123615)
- Conivaptan Impurity 5 (CAS CATO-C4X-13605)
- N-Nitroso Amoxicillin Impurity K (CAS CATO-C4X-114880)
- 4-Aminochroman-8-carbonitrile hydrochloride (CAS 911824-58-3)
- Abiraterone Impurity 42 (CAS CATO-C4X-107042)
- 3,4-Dihydro-[1,4]dioxepino[2,3-f]indole-8,9(2H,7H)-dione (CAS 847837-43-8)
- (S)-tert-Butyl 3-methyl-2-oxopiperidine-3-carboxylate (CAS 1820805-42-2)
- 3-[(2-Methylbenzyl)oxy]benzaldehyde (CAS 590350-87-1)
- 2,3-Di(9H-carbazol-9-yl)quinoxaline (CAS 2189730-32-1)
- Serpent Peptide 2AcOH (CAS 823202-99-9(free base))
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com