Bortezomib Impurity 61 CAS CATO-C4X-107261
| CAS No. | CATO-C4X-107261 |
| Molecular Formula | C14H14N4O2 |
| Molecular Weight | 270.29 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Bortezomib Impurity 61 (C14H14N4O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO supplies Bortezomib Impurity 61 (CAS CATO-C4X-107261), a pharmacopoeial impurity reference standard (molecular formula C14H14N4O2, MW 270.29 g/mol) used for the identification and quantification of trace impurities in APIs.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H14N4O2 |
| Molecular Weight | 270.29 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 4 |
Related Bortezomib Standards
- Bortezomib Impurity 1 (CAS 289472-80-6)
- Bortezomib Impurity 36 (CAS CATO-C4X-107236)
- Bortezomib Impurity 2 (CAS 114457-94-2)
- Bortezomib Impurity 31 (CAS 1608986-16-8)
- Bortezomib Impurity 80 (CAS 179324-86-8)
- Bortezomib Impurity 49 (CAS 948294-96-0)
- Bortezomib Impurity 40 (CAS 87304-47-0)
- Bortezomib Impurity N46 (CAS 85167-14-2)
Recommended Standards
- Acotiamide Impurity 30 (CAS CATO-C4X-111430)
- Pentoxifylline EP Impurity I (CAS 55247-90-0)
- Edaravone impurity 40 (CAS CATO-C4X-106240)
- Morinidazole (CAS 92478-27-8)
- Gimeracil Impurity 8 (CAS CATO-C4X-12148)
- Ambrisentan Impurity 5 (CAS 178306-51-9)
- Furazolidone Impurity 7 (CAS CATO-C4X-29017)
- n,3-Dimethylpyrrolidine-3-carboxamide (CAS 1342746-44-4)
- 3-(3-Bromo-2-methyl-6-(methylthio)phenyl)-4,5-dihydroisoxazole (CAS 250592-92-8)
- (Tetrahydrofuran-3-yl)methanethiol (CAS 51171-23-4)
- Benzydamine Hydrochloride (CAS 132-69-4)
- 1,3-Isobenzofurandione, polymer with 2,2'-oxybis[ethanol], bis(2-methyl-2-propenoate) (CAS 57657-11-1)
- 1038558-41-6 3-(5-bromothiophen-2-yl)-1H-pyrazole-5-carboxylic acid F2130-0113 (CAS 1038558-41-6)
- A-18-F-NH2; Morphine Modulating Neuropeptide (CAS 99588-52-0)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com