Bortezomib Impurity 36 CAS CATO-C4X-107236

Purity >95%In StockPharmacopoeial Impurity Standards
CAS No.CATO-C4X-107236
Molecular FormulaC14H14N4O2
Molecular Weight270.29 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Bortezomib Impurity 36 CAS CATO-C4X-107236 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 270.29 g/mol gives Bortezomib Impurity 36 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

Bortezomib Impurity 36 (CAS CATO-C4X-107236) is a certified pharmaceutical impurity reference standard with the molecular formula C14H14N4O2 and a molecular weight of 270.29 g/mol.

Based on its molecular formula C14H14N4O2, Bortezomib Impurity 36 contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 270.29 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

As a certified reference material (CRM), Bortezomib Impurity 36 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC14H14N4O2
Molecular Weight270.29 g/mol
AppearancePale yellow to yellow crystalline powder
Purity>95%
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)10.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
Nitrogen Atoms4

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