Thioctic acid Impurity 74 CAS 852383-82-5

Purity >95%In StockPharmacopoeial Impurity Standards
CAS No.852383-82-5
Molecular FormulaC10H19ClO3
Molecular Weight222.71 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Thioctic acid Impurity 74 CAS 852383-82-5 chemical structure

Description

As a certified reference material (CRM), Thioctic acid Impurity 74 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Thioctic acid Impurity 74 (CAS 852383-82-5) is a certified pharmaceutical impurity reference standard with the molecular formula C10H19ClO3 and a molecular weight of 222.71 g/mol.

Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, Thioctic acid Impurity 74 is typically white to off-white crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 222.71 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

Physical & Chemical Properties

Molecular FormulaC10H19ClO3
Molecular Weight222.71 g/mol
Purity>95%
StorageStore in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, ethanol, DMSO
StabilityHygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)1.0
CAS Registry Year (est.)1987
Halogen ContentCl-containing

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