Sorafenib Impurity 27 CAS 757251-59-5
| CAS No. | 757251-59-5 |
| Molecular Formula | C13H12N2O3 |
| Molecular Weight | 244.25 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Sorafenib Impurity 27 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
CATO supplies Sorafenib Impurity 27 (CAS 757251-59-5), a pharmacopoeial impurity reference standard (molecular formula C13H12N2O3, MW 244.25 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, Sorafenib Impurity 27 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 244.25 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C13H12N2O3 |
| Molecular Weight | 244.25 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Nitrogen Atoms | 2 |
Related Sorafenib Standards
- Sorafenib Impurity 61 (CAS 284462-78-8)
- Sorafenib EP Impurity A (CAS 284462-37-9)
- Sorafenib Impurity 54 (CAS 1153328-25-6)
- Sorafenib impurity 65 (CAS CATO-C4X-112465)
- Sorafenib Impurity 12 (CAS 343247-69-8)
- Sorafenib Impurity 15 (CAS CATO-C4X-112415)
- Sorafenib Impurity 60 (CAS 284462-86-8)
- Sorafenib Impurity 45 (CAS 46843-47-4)
Recommended Standards
- Milrinone Impurity 6 (CAS 1443528-66-2)
- Potassium Clavulanate impurity 24 (CAS 148601-28-9)
- 898765-78-1 2,2-Dimethyl-1-[2-(trifluoromethyl)phenyl]butan-1-one DTXSID80642447 (CAS 898765-78-1)
- Eltrombopag Impurity 26 (CAS CATO-C4X-119826)
- Mirogabalin Impurity 81 (CAS 1138246-18-0)
- Fosaprepitant Impurity 16 (CAS 327623-34-7)
- Darifenacin Impurity 1 (CAS 87776-76-9)
- 3-(5,5-Dimethyl-2,4-dioxoimidazolidin-1-yl)propanoic acid (CAS 1415719-25-3)
- Rivaroxaban Impurity 148 (CAS 1450877-56-1)
- Fasudil impurity 68 (CAS CATO-C4X-136568)
- 1-((4-Methoxybenzyl)amino)propan-2-ol (CAS 856978-80-8)
- 1-([1,2,4]triazolo[4,3-a]pyridin-3-ylthio)-3,3-dimethylbutan-2-one (CAS 1090492-61-7)
- 2-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-N-[(pyridin-2-yl)methyl]acetamide (CAS 691873-26-4)
- D-[Ala]24-Semaglutide (CAS CATO-C4X-2226126)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com