Sorafenib EP Impurity B CAS 2004659-84-9
| CAS No. | 2004659-84-9 |
| Molecular Formula | C14H13N3O3 |
| Molecular Weight | 271.27 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Structurally, Sorafenib EP Impurity B (C14H13N3O3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 10.0, corresponding to approximately 10 ring(s) or double-bond equivalent(s). With a molecular weight of 271.27 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO supplies Sorafenib EP Impurity B (CAS 2004659-84-9), a pharmacopoeial impurity reference standard (molecular formula C14H13N3O3, MW 271.27 g/mol) used for the identification and quantification of trace impurities in APIs.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Sorafenib EP Impurity B under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H13N3O3 |
| Molecular Weight | 271.27 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1996 |
| Nitrogen Atoms | 3 |
Related Sorafenib Standards
- Sorafenib Impurity 56 (CAS 864272-34-4)
- Sorafenib EP Impurity G (CAS 18585-06-3)
- Sorafenib Impurity 60 (CAS 284462-86-8)
- Sorafenib Impurity 11 (CAS 1129683-88-0)
- Sorafenib Impurity 29 (CAS CATO-C4X-112429)
- Sorafenib impurity 65 (CAS CATO-C4X-112465)
- Sorafenib Impurity 27 (CAS 757251-59-5)
- Sorafenib Impurity 61 (CAS 284462-78-8)
Recommended Standards
- Alogliptin Impurity 60 (CAS 2514763-78-9)
- Neratinib Impurity 40 (CAS 848133-75-5)
- Bortezomib Impurity 31 (CAS 1608986-16-8)
- Formoterol Impurity 119 (CAS CATO-C4X-1525119)
- Hydrochlorothiazide Impurity 56 (CAS CATO-C4X-117756)
- Clopidogrel Hydrochloride EP Impurity A (CAS 144750-42-5)
- Ambroxol Maillard Lactose Impurity 5(Ambroxol Impurity 74) (CAS CATO-C4X-108574)
- Cefcapene Impurity 51 (CAS CATO-C4X-182451)
- 6-CHLORO-5-FLUORO-2,3-DIHYDRO-1H-INDOLE (CAS 205584-67-4)
- 2-(Difluoromethyl)-4-fluoro-3-nitropyridine-5-acetic acid (CAS 1805437-98-2)
- Octadecanoic acid, 9-(sulfooxy)-, sodium salt (CAS 65151-76-0)
- (S)-N-(4-Iodobenzyl)-N,3-dimethyl-1-(pyrrolidin-1-yl)butan-2-amine (CAS 1416444-98-8)
- 2-(4-Amino-1h-pyrazol-1-yl)-N-cyclopropyl-N-ethylacetamide (CAS 1156730-49-2)
- Semaglutide impurity 196 (CAS CATO-C4X-2226196)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com